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Lung Transplant: Treatments

Lung transplant:

A lung transplant is a surgical procedure to replace a diseased or failing lung with a healthy lung, usually from a deceased donor. Depending on your medical condition, a lung transplant may involve replacing one of your lungs or both of them. In some situations, the lungs may be transplanted along with a donor heart.

Unhealthy or damaged lungs can make it difficult for your body to get the oxygen it needs to survive. A variety of diseases and conditions can damage your lungs and hinder their ability to function effectively, including:

Chronic obstructive pulmonary disease (COPD), including emphysema
Scarring of the lungs (pulmonary fibrosis)
Cystic fibrosis
Sarcoidosis with advanced fibrosis
Pulmonary hypertension

Lung damage can often be treated with medication or with special breathing devices. But when these measures no longer help or your lung function becomes life-threatening, your doctor might suggest a lung transplant.

HOW to Prepare:
A lung transplant is a surgical procedure to replace a diseased or failing lung with a healthy lung, usually from a deceased donor. Depending on your medical condition, a lung transplant may involve replacing one of your lungs or both of them. In some situations, the lungs may be transplanted along with a donor heart.

The number of people needing lung transplants far exceeds the number of donated lungs available. When a donor organ becomes available, the donor-recipient matching system administered by the United Network for Organ Sharing (UNOS) finds an appropriate match based on specific criteria, including:

Blood type
Size of organ compared with chest cavity
Geographic distance between donor organ and transplant recipient
Severity of the recipient’s lung disease
Recipient’s overall health
Likelihood that the transplant will be successful

While you wait

It may take months or even years before a suitable donor becomes available, but you must be prepared to act quickly when one does. Make sure the transplant team knows how to reach you at all times.

Keep your packed hospital bag handy — including an extra 24-hour supply of your medications — and arrange transportation to the transplant center in advance. You may be expected to arrive at the hospital within just a few hours.
At the hospital

Once you arrive at the hospital, you will undergo tests to make sure the lung is a good match and that you are healthy enough to have the surgery. The donor lung also must be healthy or it will be declined by the transplant team. The transplant will be canceled if it doesn’t appear that the surgery will be a success.

Risks:
Complications associated with a lung transplant can sometimes be fatal. The two major risks are rejection and infection.
Risk of rejection

Your immune system defends your body against foreign substances. Even with the best possible match between you and the donor, your immune system will try to attack and reject your new lung or lungs.

Your drug regimen after transplant will include medications to suppress your immune system in an effort to prevent organ rejection. You’ll likely take these anti-rejection drugs for the rest of your life.
Side effects of anti-rejection drugs

Anti-rejection drugs may cause noticeable side effects, including:

Weight gain
A rounder face
Acne
Facial hair
Stomach problems

Some anti-rejection medications can also increase your risk of developing new or aggravating existing conditions, such as:

Diabetes
Kidney damage
Osteoporosis
Cancer
Hypertension

Risk of infection

The anti-rejection drugs suppress your immune system, making your body more vulnerable to infections, particularly in your lungs. To help prevent infections, you should:

Wash your hands often
Take care of your teeth and gums
Protect your skin from scratches and sores
Avoid crowds and people who are ill
Receive appropriate vaccinations

Results:
A lung transplant can substantially improve your quality of life. The first year after the transplant — when surgical complications, rejection and infection pose the greatest threats — is the most critical period. Although some people have lived 10 years or more after a lung transplant, only about half the people who undergo the procedure are still alive after five years.

Article By

Fortis Hospitals

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