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Bone Cancer: Causes, Symptoms & Treatments

What Is Bone Cancer?

Bone cancer occurs when a tumor, or abnormal mass of tissue, forms in a bone. A tumor may be malignant, which means it’s growing aggressively and spreading to other parts of the body. A malignant tumor is often referred to as cancerous. Cancer that begins in the bones is rare.

Types of Bone Cancer

Primary bone cancers are the most serious of all bone cancers. They form directly in the bones or surrounding tissue, such as cartilage.

Cancer can also spread, or metastasize, from another part of your body to your bones. This is known as secondary bone cancer, and this type is more common than primary bone cancer.

Common types of primary bone cancers include:

Multiple Myeloma (MM)

Multiple myeloma is the most common type of bone cancer. It occurs when cancer cells grow in the bone marrow and cause tumors in various bones. MM usually affects older adults. Among bone cancers, MM has one of the best prognoses, and many people who have it don’t require treatment.

Osteosarcoma (Osteogenic Sarcoma)

Illustration showing osteosarcoma<br /><br /><br /><br />

Osteosarcoma, or osteogenic sarcoma, generally affects children and adolescents, but it can also occur in adults. It has a tendency to originate at the tips of the long bones in the arms and legs. Osteosarcoma may also start in the hips, shoulders, or other locations. It affects the hard tissue that provides the outer layer of your bones.

Chondrosarcoma

Chondrosarcoma may occur in the pelvis, thigh areas, and shoulders of older adults. It forms in the subchondral tissue, which is the tough connective tissue between your bones. This is the second most common primary cancer involving the bones.

Ewing’s Sarcoma

Illustration showing Ewing's sarcoma<br /><br /><br /><br />

Ewing’s sarcoma is a rare cancer that either begins in the soft tissues surrounding the bones or directly in the bones of children and young adults. The long bones of the body, such as the arms and legs, and the pelvis are commonly affected.

What Are the Symptoms of Bone Cancer?

  • pain and swelling in the affected bones
  • palpable hard mass in the long bones of the limbs
  • feeling tired or fatigued

Less common symptoms include:

  • easily broken bones
  • weight loss

What Causes Bone Cancer?

The cause of bone cancer isn’t exactly known, but there are certain factors that may contribute to or increase a person’s chances of forming abnormal growths in the bone. These include:

Abnormal Cellular Growth

Healthy cells continually divide and replace older cells. After completing this process they die. Abnormal cells, however, continue living. They start forming masses of tissue that turn into tumors.

Radiation Therapy

Radiation therapy, which kills dangerous cancer cells, can be used to treat bone cancer. However, osteosarcoma may form in some people who receive the treatment. The use of high dosages of radiation may be a factor in this development.

 Who Is at Risk for Bone Cancer?

The following may be risk factors for bone cancer:

  • having a family history of cancer, especially bone cancer
  • having received radiation treatment or therapy in the past
  • having Paget’s disease, which is a condition that causes the bones to break down and then grow back abnormally
  • currently or previously having had multiple tumors in the cartilage, which is the connective tissue in the bone

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