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Oculoplasty: Types of procedure

WHAT IS OCULOPLASTY?

Oculoplasty is the art and science of plastic surgery around the eye. The eyeball is a delicate structure, protected from harm by eyelids in front and the bony cup (socket) behind. Behind the eyeball run the nerves , arteries and muscles, which carry messages to the brain, move the eyeball, and provide nutrition to the eye. Oculoplasty deals with all these structures surrounding the eyeball.

WHY SHOULD AN EYE SURGEON DO PLASTIC SURGERY?

Oculoplastic surgeons first train as ophthalmologists, when they learn in details about the eye. During further higher training, they start to handle plastic surgery. They have the best knowledge about the eye and its surrounding; as eye surgeons, they are also ready to handle the most delicate of structures. This combination of skills makes the oculoplastic surgeons the best to do plastic surgery around the eye.

Types of Surgeries:

  • Ptosis:  Ptosis is drooping of the upper lid. It may be present by birth, or appear later in life. Ptosis is usually corrected by surgery.
  • Entropion– Entropion is in-turning of the eyelid. The eyelashes rub on the eye and cause pain and watering; treatment is by surgery, Ectropion– Ectropion is turning outwards of the eyelid margin, causing redness and watering (Link to gallery)Lagophthalmos- where the patient cannot close his eye; this can cause danger to the eye, pain and infection.
  • Eyelid tumors: Lid tearrepairs with grafts and flaps
  • ORBIT: Orbital fractures– A fracture in the bones around the eye can cause double vision, and a sunken small appearance of the eye. The fracture is repaired with an implant or plate. The best results are obtained in surgery within 2 weeks of injury, but surgery can also be done later.

 

Schizophrenia : Causes, symptoms & treatments

What is Schizoaffective Disorder?

Schizoaffective disorder is a mental disorder in which the individual reflects symptoms that occur both in schizophrenia and mood disorder (major depressive or bipolar disorder). However, studies suggest that schizoaffective disorder resembles schizophrenia more than bipolar disorder. According to a report by National Alliance on Mental Illness, schizoaffective disorder is observed in about 0.3% of the population. Men and women experience schizoaffective disorder equally, but men are often reported to develop it at an earlier age.

Schizophrenia

Schizophrenia is a severe mental disorder that affects about 21 million people worldwide. It is characterized by distortions in thinking, perception, emotions, language, sense of self and behavior.

Bipolar and major depressive disorder

Bipolar disorder has been estimated to affect about 60 million people worldwide. It typically includes both manic and depressive episodes separated by periods of normal mood. The main difference between bipolar disorder and depressive disorder are the mania symptoms. When mood swings between manic and depressed states occur, it is referred to as bipolar disorder and when depression occurs alone it is a unipolar in nature, as it does not involve mania.

Mixed type- In this type of schizoaffective disorder the person has symptoms of schizophrenia, depression and mania.

What are the Causes of Schizoaffective Disorder?

The exact cause of schizoaffective disorder is unknown. But the following causes are the main factors. They include:

  • Genetics: Schizoaffective disorder tends to run in patients with a family history of the condition. It is not necessary that a person with a family history will continue to have the illness but there is a greater chance of them developing the illness. Studies reveal that it shows substantial familial overlap with both schizophrenia and bipolar disorder.
  • Brain chemistry and structure: Brain function and structure play an important role in the etiology of schizoaffective disorder. It may be induced by a neurotransmitter imbalance in a feedback-regulated system. It may involve imbalances in neurotransmitters such as dopamine, serotonin, norepinephrine, and glutamate that help regulate mood.
  • Stress: Stressful events or trauma such as early parental loss, any family conflict, or physical or sexual abuse can trigger symptoms or an onset of the illness. This is more likely to be a cause if one had experienced any such triggers when he or she was too young to know how to cope with them.
  • Environmental factors: Some factors like malnutrition, maternal illness or prenatal exposure to toxins may also cause schizoaffective disorder.
  • Drug or substance use: Psychoactive drugs such as LSD (Lysergic Acid) have been linked to the development of schizoaffective disorder. Also, cannabis use especially before the age of 15 years has also been reported to be a causative agent for this disorder.

What are the Signs and Symptoms of Schizoaffective Disorder?

The specific symptoms themselves may vary from person to person but the main symptoms include:

  • Hallucinations- Imagining, seeing, hearing, or even smelling things that do not actually exist.

  • Delusions- Having fixed, false beliefs inspite of having a strong evidence against them. It also includes delusions of persecution like believing that they are threatened, spied or attacked by someone.

  • Disorganized thinking- A person may switch very quickly from one topic to another unrelated topic and might have trouble organizing his thoughts and connecting them with a logical base.
  • Catatonic behavior- It may include bizarre behaviors and overall disability in performing daily activities such as bathing, dressing properly or even eating regularly.
  • Depressed mood- If a person has been diagnosed with schizoaffective disorder depressive type then they may have loss of interest in things they used to like before. Insomnia or hypersomnia is also observed.
  • Manic behavior- The person may also experience feelings of euphoria, inflated self-esteem, racing thoughts, increased risky behavior and other symptoms of mania.

Some physical symptoms are also observed; they include:

  • Changes in physical appearance
  • Poor hygiene
  • Significant weight loss
  • Psychomotor agitation
  • Fatigue or loss of energy

What are the Complications of Schizoaffective Disorder?

Individuals who have schizoaffective disorder that remains untreated or improperly diagnosed may run the risk of developing numerous complications. Examples may include:

  • Substance use and abuse
  • Onset of self-harming behaviors
  • Co-occurring Disorders

The most commonly occurring disorders alongside schizoaffective disorder are:

  • Post traumatic stress disorder (PTSD)
  • Generalized anxiety disorder
  • Obsessive compulsive disorder
  • Obesity
  • Diabetes

How do you Treat Schizoaffective Disorder?

Schizoaffective disorder can be managed effectively with medication and therapy. It belongs to the category of recurrent disorders and therefore, needs prophylactic treatment. National Institute for Health and Care Excellence (NICE) recommends that one should be treated with a combination of medication and talking therapies.

Medications-Certain medications are offered first, especially if an individual is first diagnosed during a psychotic episode.


It includes:

  • An antipsychotic drug- such as olanzapine or quetiapine.
  • mood stabilizer- such as lithium or valproate – especially if you have manic episodes rather than depression. Lamotrigine, is prescribed in case of bipolar disorder.
  • An anti-depressant- is used in case of symptoms that switch between mania and depression. Combination of anti-depressants with anti-psychotics are also used; for example, sertraline or fluoxetine plus haloperidol or risperidone.

Cognitive behavior therapy (CBT) – It acts as an add-on to medication and can help a person cope with the illness in a better way. It focuses on a person’s thoughts, beliefs, and how these affect their mood and actions. It also helps to identify and change any negative thoughts or behavior and replace them with adaptive thoughts.

Back Acne: Causes, prevention & Treatment

Causes

There are two causes of back acne: an increase in oil production or irritated skin. When your skin glands produce too much oil due to stress, genetics, hormonal imbalance or a poor diet, the increase in oil overproduction can clog up your skin follicles, preventing dead skin from escaping. This allows bacteria to breed and acne breakouts to occur. When clothing is warm and tight against the skin, acne may thrive because tight clothing can also trap dead skin cells. Tight clothing or a wearing a backpack may aggravate back acne by spreading the bacteria, causing fresh outbreaks.

Prevention

Wearing loose, cotton clothing may help prevent the spread of back acne. Instead of wearing a backpack, carry a handheld bag to decrease skin irritations on your back. Wash the skin on your back, regularly and immediately after exercise — but do not shower more than twice a day. Excessive bathing or showering may dry and irritate the skin on your back. To reduce the bacteria production on your skin’s surface, use an antibacterial soap daily. Exfoliate your back with a sugar-based scrub a few times a week to remove dead skin cells that may clog your follicles. Do not wear shirts more than once and keep bed sheets clean. If you sweat a lot, wipe your back with a soft towel regularly.

Treatment

Because the skin on your back is tougher and denser than the skin on your face, treatments differ depending on the severity of your back acne. If you have mild back acne and washing the skin regularly is not enough to control it, topical treatments sold in drugstores may kill bacteria, dry the oil and remove dead skin cells. If over-the-counter treatments are too weak, a doctor may prescribe a topical cream for moderate cases of acne. In severe cases, Accutane may be prescribed. This medication comes in pill form and is derived from Vitamin A. Accutane has the power to shrink oil glands, but comes with serious side effects, such as dry eyes and lips, aching joints, itching and blurred vision. If your back acne leads to scars or cysts, you may be a candidate for laser treatment or surgery, but consult your doctor before scheduling any procedures.

Considerations

If you get red marks or irritations on your back, check with your doctor to ensure you are suffering from acne and not eczema, as this requires a completely different treatment.

Hair Transplant surgery: Types & Steps

Hair transplant surgery is surgery that is performed to restore hair to areas of the scalp that are bald or that have thinning hair. There are multiple types of hair replacement surgery. Most commonly, these involve hair transplantation, but flap surgery, tissue expansion of the scalp and scalp reduction surgery, are also methods used for hair replacement. Each of these types of surgeries can be used alone, or in combination, to provide the patient with the best possible outcome for hair replacement.

Hair transplantation involves removing small pieces of hair-bearing scalp from a donor site and using them as grafts to be relocated to a bald or thinning area of the scalp.

Flaps surgeries involve moving hair bearing scalp tissue into bald areas of the scalp.

Tissue expansion allows the hair bearing scalp to be expanded to help cover areas of the scalp that have no hair.

Scalp reduction surgery involves surgically removing bald areas of the scalp and advancing, or bringing together, the hair bearing areas of the scalp.

If you and your surgeon have determined that hair transplant surgery is the best option for you, you can feel comfortable knowing that board-certified plastic surgeons have been successfully performing these types of procedures for more than thirty years.

The truth about hair loss

Baldness is often blamed on poor circulation to the scalp, vitamin deficiencies, dandruff and even excessive hat wearing. All of these theories have been disproved. It’s also untrue that hair loss can be determined by looking at your maternal grandfather, or that 40-year-old men who haven’t lost their hair will never lose it.

Hair loss is primarily caused by a combination of:

  • Aging
  • A change in hormones
  • A family history of baldness

Hair transplantation steps:

Hair transplantation involves removing small punch grafts from the hair bearing scalp or a larger piece of this scalp from a donor area and cutting this into smaller pieces to use as grafts. These grafts are then relocating to a bald or thinning area of the scalp. The grafts created in this manner differ in size and shape. Round-shaped punch grafts usually contain about 10-15 hairs. The much smaller mini-graft contains about two to four hairs; and the micro-graft, one to two hairs. Slit grafts, which are inserted into slits created in the scalp, contain about four to 10 hairs each; strip grafts are long and thin and contain 30-40 hairs.

Generally, several surgical sessions may be needed to achieve satisfactory fullness, and a healing interval of several months is usually recommended between each session. It may take up to two years before you see the final result with a full transplant series. The amount of coverage you’ll need is partly dependent upon the color and texture of your hair. Coarse, gray or light-colored hair affords better coverage than fine, dark-colored hair. The number of large plugs transplanted in the first session varies with each individual, but the average is about 50. For mini-grafts or micro-grafts, the number can be up to 700 per session.

Just before surgery, the “donor area” will be trimmed short so that the grafts can be easily accessed and removed. For punch grafts, your doctor may use a special tube-like instrument made of sharp carbon steel that punches the round graft out of the donor site so it can be replaced in the area to be covered—generally the frontal hairline. For other types of grafts, your doctor will use a scalpel to remove small sections of hair-bearing scalp, which will be divided into tiny sections and transplanted into tiny holes or slits within the scalp. When grafts are taken, your doctor may periodically inject small amounts of saline solution into the scalp to maintain proper skin strength. The donor site holes may be closed with stitches—for punch grafts, a single stitch may close each punch site; for other types of grafts, a small, straight-line scar will result. The stitches are usually concealed with the surrounding hair.

To maintain healthy circulation in the scalp, the grafts are placed about one-eighth of an inch apart. In later sessions, the spaces between the plugs will be filled in with additional grafts. Your doctor will take great care in removing and placement of grafts to ensure that the transplanted hair will grow in a natural direction and that hair growth at the donor site is not adversely affected.

After the grafting session is complete, the scalp will be cleansed and covered with gauze. You may have to wear a pressure bandage for a day or two. Some doctors allow their patients to recover bandage-free.

Tissue Expansion

Another technique used in the treatment of baldness is called tissue expansion. Plastic surgeons are the leaders in tissue expansion, a procedure commonly used in reconstructive surgery to repair burn wounds and injuries with significant skin loss. Its application in hair transplant surgery has yielded dramatic results-significant coverage in a relatively short amount of time.

In this technique, a balloon-like device called a tissue expander is inserted beneath hair-bearing scalp that lies next to a bald area. The device is gradually inflated with salt water over a period of weeks, causing the skin to expand and grow new skin cells. This causes a bulge beneath the hair-bearing scalp, especially after several weeks.

When the skin beneath the hair has stretched enough-usually about two months after the first operation-another procedure is performed to bring the expanded skin over to cover the adjacent bald area. For more information about tissue expansion, ask your plastic surgeon for the American Society of Plastic Surgeons, Inc. brochure entitled, Tissue Expansion: Creating New Skin from Old.

Flap Surgery

Flap surgery on the scalp has been performed successfully for more than 20 years. This procedure is capable of quickly covering large areas of baldness and is customized for each individual patient. The size of the flap and its placement are largely dependent upon the patient’s goals and needs. One flap can do the work of 350 or more punch grafts.

A section of bald scalp is cut out and a flap of hair-bearing skin is lifted off the surface while still attached at one end. The hair-bearing flap is brought into its new position and sewn into place, while remaining “tethered” to its original blood supply. As you heal, you’ll notice that the scar is camouflaged—or at least obscured—by relocated hair, which grows to the very edge of the incision.

In recent years, plastic surgeons have made significant advances in flap techniques, combining flap surgery and scalp reduction for better coverage of the crown; or with tissue expansion, to provide better frontal coverage and a more natural hairline.

Scalp Reduction

This technique is sometimes referred to as advancement flap surgery because sections of hair-bearing scalp are pulled forward or “advanced” to fill in a bald crown.

Scalp reduction is for coverage of bald areas at the top and back of the head. It’s not beneficial for coverage of the frontal hairline. After the scalp is injected with a local anesthetic, a segment of bald scalp is removed. The pattern of the section of removed scalp varies widely, depending on the patient’s goals. If a large amount of coverage is needed, doctors commonly remove a segment of scalp in an inverted Y-shape. Excisions may also be shaped like a U, a pointed oval or some other figure.

The skin surrounding the cut-out area is loosened and pulled, so that the sections of hair-bearing scalp can be brought together and closed with stitches. It’s likely that you’ll feel a strong tugging at this point, and occasional pain.

Procedure Steps

Before: Hair transplant candidates should have some noticeable hair loss with healthy hair growth at the back and sides of the head to serve as donor areas.
hair transplant

Step 1: A tube-like instrument punches round grafts from the donor site to be placed in the area where hair replacement is desired.
hair transplant

Step 2: A tube-like instrument punches round grafts from the donor site to be placed in the area where hair replacement is desired.
hair transplant

Step 3: When the skin beneath the hair has stretched enough, it is surgically placed over the bald area.
hair transplant

Step 4: During flap surgery, a section of bald scalp is cut out and a flap of hair-bearing skin is sewn into its place.
hair transplant

Step 5: The patterns used in scalp reduction vary widely, yet all meet the goal of bringing hair and scalp together to cover bald areas.
hair transplant

After: The results of hair transplant surgery can enhance your appearance and self-confidence.

Umbilical Hernia: Causes, symptoms & treatments

Umbilical Hernia

  • It is a common type of Hernia and constitutes around 25% of all Hernia cases.
  • Umbilical Hernia is often noted at birth as a protrusion at the bellybutton (the umbilicus).
  • Umbilical Hernia is caused due to weakened opening in the abdominal wall, which should normally close before birth but fails to close completely.

 

 

Umbilical Hernia

Causes of umbilical hernia in adults

Umblical hernia that is acquired happens due to intra-abdominal pressure from lifting heavy objects, multiple pregnancies, long history of coughing and obesity.

During pregnancy, the umbilical cord traverses through a little opening or belly button in the baby’s abdominal muscles. This slit normally closes just prior to the birth. If the muscles do not join properly in the middle line of the abdomen, the weakness of the abdominal wall can result in umbilical hernia either at that time or later in life.

Complications of umbilical hernia in adults

Adults who have umbilical hernia are likely to experience intestinal obstruction. In such a case, emergency surgery may be needed. In case of children, the complications are not so common, and they happen only when the abdominal tissue is incarcerated and cannot be retracted into the abdominal cavity. This results in reduced blood supply to the trapped intestine leading to pain in the umbilical area and damage.

 

Umbilical hernia in adults diagnosis

In the physical exam, the doctor will ask you to do blood tests and imaging studies like an X-ray or abdominal ultrasound may be done to find out complications.

Importantly this type of hernia must be distinguished from a paraumbilical hernia, which occurs in adults and involves a defect in the midline near to the umbilicus, and from omphalocele.

Umblical Hernia in adults Treatment

When the hole is small, say less than 1 or 2 centimeters, it is believed that 90 percent of umbilical hernia cases close in three years. If hernias do not enlarge or are asymptomatic, then there may or may not be a need for surgery.

When is surgery required for umbilical hernia?

In adults, surgery is required as a part of umbilical hernia treatment, epscially if the said hernia becomes bigger or causes pain. During surgery, a little incision is made below the navel. The herniated tissue is pushed back to the abdominal cavity, and the gap in the abdominal wall is stitched. People can go to work within a few hours of surgery and normal activities can be resumed in two to four weeks.

In children,umbilical hernia surgery is needed only if the hernia is large and cause pain. The doctor suggest operation when the hernia gets bigger after the age of 1 or 2 of it is seen to be blocking the intestines.

 

Spigelian Hernias: Causes, Symptoms & Treatments

Spigelian hernias often begin around the tissue line which is located on either side of the Rectus Abdominis. One among many other reasons of such kind of hernia is weakening of the abdominal wall. Such kind of weakness occur especially later in life. Other causes can include injury or because of prolonged periods of physical stress.

Mostly spigelian hernia is confuse with another type of problem abdominally. As mentioned above, this type of hernia develop through a weakness between the muscle fibres of the abdominal wall. This protrusion may contain a section of the intestines but in other cases it takes the form of an empty sac. it often develop on the right hand side of the abdomen. Du e to its location, no obvious swelling or lump is there which can make it almost impossible to detect. As a consequent, many people with this type of hernia do not even realize that they actually developed a hernia which means that it may remains undetected for a long period of time.

Spigelian hernia is considered rare type of hernia which occurs in both men and women alike. It often develops later on in life when the abdominal muscles are not strong and becoming weak. Beside this, they may occur from the same causes of other types of hernias which include any sport that involve excessive twisting or turning, Chronic coughing e.g. from smoking as well as overweight. They are normally located in between the layers of muscles in the wall of the abdomen and easily can be overlooked due to obesity in this area.

Spigelian Hernia Symptoms

The major issue that is generally associated with hernia is their location to develop. Almost all types of hernia are located subcutaneously beneath the fat layers. Although their identification is also difficult but swelling can show that here is something abnormal. But in case of spigelian hernia, it is more complex, because it is found inside the muscles of the walls of the abdomen. Since it is a hernia that is sub-muscular, there is not any external swelling sign or bump with this type of hernia.

Besides having no swelling, this kind of hernia is normally very tiny, adding to the difficulty in identifying. The common indicators of this type of hernia are intermittent mass as well as abdominal discomfort. The only sign that make them a bit obvious is pain, only noticeable sign in the actual location. Pain comes and goes on a repeated basis. In terms of size, it is small, and the external soft tissue mass or lump may be felt by the individual, who has little fat in the area that is affecting the abdomen. In addition to pain, which is the only obvious symptom, Irregular or decrease bowel and this tends to remain for more than only one day, can also be a symptom in some patients.

Spigelian Hernia Diagnoses

Because of the absence of obvious symptoms, this medical problem is extremely hard to diagnose. Mostly it stays concealed for a longer period of time. Usually a good medical exam along with imaging tests are done to diagnose it. Imaging tests are essential to eliminate the doubt for other health conditions. CT scan results can confirm its presence.

Spigelian Hernia Causes

Following are some important causes of Spigelian Hernia:

  • They are also known as spontaneous hernias since they often created suddenly after trauma or injury to the abdomen area.
  • Chronic coughing can also cause Spigelian hernia.
  • Over weight is generally considered as one major cause of this type of hernia. So keep yourself away from obesity.
  • Tough sport like heavy weight lifting can also cause this medical condition.
  • An inborn defect of connecting tissue, post-surgery infection, pregnancy, abdominal fluid as well as straining during bowel movement or urination are some other causes which may relate with its causes.

Spigelian Hernia Treatment

Surgery is only treatment that can repair this type of hernia, since it is prone to strangulation. Conventional or laparoscopic surgery might be carried out to put any organs that were displaced back in correct place once the contents are detached from the hernia for suturing. The abdominal wall that is injured is toughened with a surgical mesh to stop any recurrence. If this mesh is not in place, the hernia will be more likely to return.

Patient’s recovery time is relatively short , usually two weeks. The laparoscopic method is usually favored in order to minimize any chances of infection as well as reduce the stay in the hospital. A post-surgery follow-up exam with the attending surgeon is common in order to avoid any complications.

Hormone imbalence in womens: Causes & symptoms

Feeling bloated, irritable, or just not your best? A hormone imbalance could be to blame. Hormones are chemical “messengers” that impact the way your cells and organs function. It’s normal for your levels to shift at different times of your life, such as before and during your period or a pregnancy, or during menopause. But some medications and health issues can cause them to go up or down, too.

Irregular Periods

Most women’s periods come every 21 to 35 days. If yours doesn’t arrive around the same time every month, or you skip some months, it might mean that you have too much or too little of certain hormones (estrogen and progesterone). If you’re in your 40s or early 50s — the reason can be perimenopause — the time before menopause. But irregular periods can be a symptom of health problems like polycystic ovarian syndrome (PCOS).

Sleep Problems

If you aren’t getting enough shut-eye, or if the sleep you get isn’t good, your hormones could be at play. Progesterone, a hormone released by your ovaries, helps you catch zzz’s. If your levels are lower than usual, that can make it hard to fall and stay asleep. Low estrogen can trigger hot flashes and night sweats, both of which can make it tough to get the rest you need.

CNS Lymphoma: Causes, Symptoms & Treatments

Central nervous system lymphoma is a rare non-Hodgkin lymphoma in which malignant (cancer) cells from lymph tissue form in the brain and/or spinal cord (primary CNS) or spread from other parts of the body to the brain and/or spinal cord (secondary CNS). Because the eye is so close to the brain, primary CNS lymphoma can also start in the eye (called ocular lymphoma). The cancer can also involve the spinal fluid that bathes the spinal cord and brain. This is called leptomeningeal lymphoma.

Both primary and secondary CNS lymphomas are rare diseases. The cancer is a form of extranodal, high-grade non-Hodgkin B-cell lymphoma. Most forms of CNS lymphoma (about 90 percent) are diffuse large B-cell lymphomas; the remaining ten percent are poorly characterized low-grade lymphomas, Burkitt lymphomas and T-cell lymphomas.

Central nervous system lymphoma is more common in men than women. The median age of diagnosis is 55; the median age of AIDS-infected patients with primary CNS lymphoma is 35.

Causes and Risk Factors

Although the exact causes of CNS lymphoma are not known, there are several factors that may increase a person’s risk for developing the disease, such as having a compromised immune system due to acquired immunodeficiency syndrome (AIDS), other disorders of the immune system, or chronic immunosuppression (a reduced function of the immune system) as a result of organ transplantation.

Symptoms

The symptoms of CNS lymphoma depend on the location of the tumor. Patients may experience nausea and vomiting, leg and arm weakness, seizures, headaches, changes in mental alertness or confusion, facial weakness, double vision and hearing loss and/or swallowing difficulties. Patients with ocular lymphoma may notice blurry vision and patients with lymphoma involving their spinal cord or spinal fluid may experience back pain, leg weakness or incontinence.

Diagnosis

Tests that examine the eyes, brain and spinal cord are used to find and diagnose CNS lymphoma. These tests may include

  • Physical exam and history
  • Neurological exam to check mental status, coordination, ability to walk normally and how well the muscles, senses and reflexes work
  • Slit-lamp eye exam – This test uses a special microscope with a bright, narrow slit of light to check the outside and inside of the eye.
  • Vitrectomy – A surgical procedure in which some of the vitreous humor (the gel-like fluid inside the eyeball) is removed and examined under a microscope to check for cancer cells.
  • Chest x-ray and CT scans of the chest and abdomen
  • MRI scans of the brain and spinal cord
  • Blood and urine tests
  • Lumbar puncture (or spinal tap)
  • Stereotactic biopsy, in which a computer and a three-dimensional scanning device are used to find a tumor and guide the removal of tissue for examination under a microscope to look for cancer cells.

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Staging

After CNS lymphoma is diagnosed, a series of tests may be done to determine whether the cancer has spread. The information is then used to stage the disease and plan treatment. At this time, patients may also want to schedule a consultation with an ophthalmologist (eye doctor).

Some tests used to stage CNS lymphoma include:

  • CT scan
  • PET scan
  • Bone marrow aspiration and biopsy

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  • Slit-lamp eye exam
  • Vitrectomy
  • Testicular examination in men

Prognostic Factors

There are certain factors that affect prognosis (the chance of recovery) and treatment options for CNS lymphoma. These include

  • The patient’s age and overall health
  • Performance status
  • Lactate dehydrogenase level
  • Unusually higher or lower level of certain substances in the blood and cerebrospinal fluid
  • Location of the tumor in the central nervous system
  • Whether the patient has AIDS

Treatment

There is no standard treatment for CNS lymphoma. Your doctor will discuss the best treatment option for you. As CNS lymphoma only affects a small number of people, it is important to be treated by a hematologist/oncologist who is knowledgeable about non-Hodgkin lymphoma. It is important to consider getting a second opinion with a NHL expert to make sure you are aware of all treatment options.

Possible treatment options are listed below. Methotrexate-based combinations have been the most successful for CNS lymphoma patients. These are usually given at high doses and require that the patient be hospitalized while giving the chemotherapy. For patients over age 60 years, radiation treatment can be extremely neurotoxic and it is important to speak to your doctor before receiving this treatment. Patients who have relapsed or refractory CNS lymphoma, cytarabine and topotecan may also be an option. Talk to your doctor about the best care for you.

Treatment options for CNS lymphoma not related to AIDS include:

  • Chemotherapy
  • Chemotherapy followed by radiation therapy
  • Steroid therapy
  • Whole brain radiation therapy
  • A clinical trial of high-dose chemotherapy with stem cell transplant

Treatment options for AIDs-related CNS lymphoma include:

  • Steroids with or without radiation
  • Radiation
  • Chemotherapy followed by radiation therapy

Treatment for recurrent (the cancer comes back) CNS lymphoma includes:

  • Chemotherapy or radiation (if not received as first-line treatment)
  • Chemotherapy and radiation
  • A clinical trial

For some patients, taking part in a clinical trial may be the best treatment choice. There are also several clinical trials available nationally that are examining the role of radiation and the role of bone marrow transplantation for the treatment of primary CNS lymphoma. Your doctor can discuss if these clinical trials are appropriate or available for you. For information about clinical trials for CNS lymphoma, please call our Information Specialists or click here for an online clinical-trial search service supported by LLS that offers patients and caregivers immediate access to listings of blood cancer clinical trials.

Treatment Outcomes

Treatment of CNS lymphoma is most effective when the tumor has not spread outside the cerebrum (the largest part of the brain) and the patient is under age 60, able to maintain daily functions and does not have AIDS or other diseases that weaken the immune system.

Actinic keratosis: Causes, Symptoms & Treatment

As you get older, you may begin to notice rough, scaly spots appearing on your hands, arms, or face. These spots are called actinic keratoses, but they’re commonly known as sunspots or age spots.

Actinic keratoses usually develop in areas that’ve been damaged by years of sun exposure. They form when you have actinic keratosis (AK), which is a very common skin condition.

AK occurs when skin cells called keratinocytes start to grow abnormally, forming scaly, discolored spots. The skin patches can be any of these colors:

  • brown
  • tan
  • gray
  • pink

They tend to appear on the parts of the body that get the most sun exposure, including the following:

  • hands
  • arms
  • face
  • scalp
  • neck

Actinic keratoses aren’t cancerous themselves. However, they can progress to squamous cell carcinoma (SCC), though the likelihood is low.

When they’re left untreated, up to 10 percent of actinic keratoses can progress to SCC. SCC is the second most common type of skin cancer. Due to this risk, the spots should be regularly monitored by your doctor or dermatologist.

What causes actinic keratosis?

AK is primarily caused by long-term exposure to sunlight. You have a higher risk of developing this condition if you:

  • are over age 60
  • have light-colored skin and blue eyes
  • have a tendency to sunburn easily
  • have a history of sunburns earlier in life
  • have been frequently exposed to the sun over your lifetime
  • have human papilloma virus (HPV

 

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What are the symptoms of actinic keratosis?

Actinic keratoses start out as thick, scaly, crusty skin patches. These patches are usually about the size of a small pencil eraser. There might be itching or burning in the affected area.

Over time, the lesions can disappear, enlarge, remain the same, or develop into SCC. There’s no way of knowing which lesions may become cancerous. However, you should have your spots examined by a doctor promptly if you notice any of the following changes:

  • hardening of the lesion
  • inflammation
  • rapid enlargement
  • bleeding
  • redness
  • ulceration

Don’t panic if there are cancerous changes. SCC is relatively easy to diagnose and treat in its early stages.

How is actinic keratosis diagnosed?

Your doctor may be able to diagnose AK simply by looking at it. They may want to take a skin biopsy of any lesions that look suspicious. A skin biopsy is the only foolproof way to tell if lesions have changed into SCC.

How is actinic keratosis treated?

AK may be treated in the following ways:

Excision

Excision involves cutting the lesion from the skin. Your doctor may choose to remove extra tissue around or under the lesion if there are concerns about skin cancer. Depending on the size of the incision, stitches may or may not be needed.

Cauterization

In cauterization, the lesion is burned with an electric current. This kills the affected skin cells.

Cryotherapy

Cryotherapy, also called cryosurgery, is a type of treatment in which the lesion is sprayed with a cryosurgery solution, such as liquid nitrogen. This freezes the cells upon contact and kills them. The lesion will scab over and fall off within a few days after the procedure.

Topical medical therapy

Certain topical treatments such as 5-fluorouracil (Carac, Efudex, Fluoroplex, Tolak) cause inflammation and destruction of the lesions. Other topical treatments include imiquimod(Aldara, Zyclara) and ingenol mebutate (Picato).

Phototherapy

  • During phototherapy, a solution is applied over the lesion and the affected skin. The area is then exposed to intense laser light that targets and kills the cells. Common solutions used in phototherapy include prescription medications, such as aminolevulinic acid(Levulan Kerastick) and methyl aminolevulinate cream (Metvix).

How can you prevent actinic keratosis?

The best way to prevent AK is to reduce your exposure to sunlight. This will also help minimize your risk of skin cancer. Remember to do the following:

  • Wear hats and shirts with long sleeves when you’re in bright sunlight.
  • Avoid going outside at midday, when the sun is brightest.
  • Avoid tanning beds.
  • Always use sunscreen when you’re outside. It’s best to use a sunscreen with a sun protection factor (SPF) rating of at least 30. It should block both ultraviolet A (UVA) and ultraviolet B (UVB) light.

It’s also a good idea to examine your skin regularly. Look for the development of new skin growths or any changes in all existing:

  • bumps
  • birthmarks
  • moles
  • freckles

Make sure to check for new skin growths or changes in these places:

  • face
  • neck
  • ears
  • the tops and undersides of your arms and hands

Schedule an appointment with your doctor as soon as possible if you have any worrisome spots on your skin.

BOW LEG: Causes, Treatment and Prevention

What Causes Bow Legged?

Bowlegs is a condition in which your legs appear bowed-out, meaning your knees stay wide apart even when your ankles are together. Bowlegs can sometimes be a sign of an underlying disease, such as Blount’s disease or rickets, and in the long term can lead to arthritis in the knees and hips. Treatment options include braces, casts, or surgery to correct these bone abnormalities.

This condition is fairly common in infants because of their cramped position in the womb. Typically, no treatment is necessary for infants. A child’s legs will begin to straighten when they start to walk, usually between 12-18 months, and in most cases there are no lasting side effects. You should contact a doctor if your child has bowlegs beyond the age of 2.

Bowleggedness is also known as congenital genu varum.

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Causes of Bowlegs

Blount’s Disease

In Blount’s disease, which is also called “tibia vara,” a child’s shin abnormally develops, curving below the knees. As your child starts to walk, the bowing of the legs becomes worse. This condition may be apparent early on but in some cases symptoms may not be noticeable until they reach adolescence. Over time, bowlegs can lead to joint problems in their knees.

Blount’s disease is more common in females and African-Americans, and obese children. Children who begin walking early are at a greater risk. A child should normally start walking on their own between 11 and 14 months of age.

Rickets

Rickets is a condition resulting from prolonged vitamin D deficiency. This softens and weakens the bones, causing your legs to bow.

Paget’s Disease

This metabolic disease negatively affects the way your bones break down and rebuild. As a result, they do not rebuild as strongly as they should, and over time this can lead to bowlegs and other joint problems. Paget’s disease is more common in older people and can be successfully managed with early diagnosis and treatment.

Dwarfism

The most common form of dwarfism is caused by a condition known as achondroplasia. This is a bone growth disorder that can result in bowlegs over time.

Other Causes

Bowlegs can also be a result of:

  • bone fractures that have not healed properly
  • abnormally-developed bones, or bone dysplasia
  • lead poisoning
  • fluoride poisoning

Recognizing the Symptoms of Bowlegs

This is a very recognizable condition. Your knees will not touch when you stand with your feet and ankles together. Bowlegs will look symmetrical.

In children, most bowleg cases start to improve when a child reaches 12-18 months old. You should talk to your pediatrician if your child’s legs are still bowed beyond the age of two, or if the condition becomes worse.

Diagnosing Bowlegs

Bowed legs are easy to spot, but your doctor can tell you how severe the condition is or whether it is caused by an underlying disease.

During your visit, your doctor will likely take your leg measurements and observe your walk. They may also order an X-ray or other imaging tests of your legs and knees to view any bone abnormalities, and blood tests to confirm your bowlegs are caused by another condition such as rickets or Paget’s disease.

Treatment of Bowlegs

Treatment is usually not recommended for infants and toddlers unless an underlying condition has been identified. Treatment may be recommended if your case of bowlegs is extreme or getting worse, or if an accompanying condition is diagnosed. Treatment options include:

  • special shoes
  • braces
  • casts
  • surgery to correct bone abnormalities
  • treatment of diseases or conditions that cause bowlegs

Can Bowlegs Be Prevented?

There is no known prevention for bowlegs. In some cases, you may be able to prevent certain conditions that cause bowlegs, for example, you can prevent rickets by making sure your child receives sufficient vitamin D, both in their diet and from exposure to sunshine. Be sure to talk to your pediatrician if your child still has bowlegs after the age of two.

Early diagnosis and detection of bowlegs will help you and your child manage this condition.

While arthritis is the primary long term effect of bowleggedness, it can be extremely disabling.  When it is severe,  it effect the knees, the feet, ankles and the hip joints because of the abnormal stresses applied.  These people are typically obese which compounds the problem.  If one is forced to do total knee replacement at a young age, then it is anticipated that a revision would have to be done when the patient is older.  Doing a total knee arthroplasty in these people may be difficult because of the surgeries they have already undergone and because of the abnormal alignment of the bones.

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