What Is Squamous Cell Cancer?

What Causes Squamous Cell Cancer?

Often pseudocysts get better and go away on their own. If a pseudocyst is small and not causing serious symptoms, a doctor may want to monitor it with periodic CT scans. If the pseudocyst persists, gets larger, or causes pain, it will require surgical treatment. If not monitored or treated, a pseudocyst can become infected or rupture, causing severe pain, blood loss and abdominal infection.

For pseudocysts requiring treatment, surgery is usually necessary. During surgery to correct a pseudocyst, the surgeon usually makes a connection between the pseudocyst and a nearby digestive organ. This allows the pseudocyst to drain through that organ. Depending on the location of the pseudocyst within the pancreas, that connection may be with the stomach, small intestine, or duodenum, the upper end of the small intestine.

In some cases, this surgery is done laparoscopically. That means it’s performed through small incisions in the abdomen, using slender tools and a lighted scope. This procedure minimizes hospitalization and recovery time.

Mycosis fungoides

Mycosis fungoides (MF), also known as Alibert-Bazin syndrome, is a low-grade type of non-Hodgkin lymphoma in which white blood cells called lymphctyes become cancerous and affect the skin. Mycosis fungoides, named because of the mushroom fungus look of advanced stages of the disease, is a T-cell lymphoma. MF is more common in men than women. Most patients are in their 50s and 60s. MF generally affects the skin, but may progress to internal organs or the lymph nodes.

Common mycosis fungoides symptoms

Mycosis fungoides is the most common type of skin lymphoma. Its symptoms vary from patient to patient. MF is often mistaken for eczema, psoriasis or dermatitis, making it difficult to diagnose at first. Several biopsies may be needed to confirm the diagnosis. Symptoms include:

• Rash
• Tumors
• Skin lesions
• Patches
• Itching

NOTE: These symptoms may be attributed to a number of conditions other than cancer. It is important to consult with a medical professional for an accurate diagnosis.

Advanced treatments for mycosis fungoides

Common mycosis fungoides treatments include:

Chemotherapy: For patients with refractory disease, chemotherapy may be provided as a single drug or a combination of drugs. Some chemotherapy drugs may be used to treat earlier forms of skin lymphoma, as topical ointments or creams applied directly to the skin.

Radiation: External beam radiation therapy (EBRT) may be used to treat mycosis fungoides. One method for delivering the radiation involves treating the skin over the whole body with rays of tiny particles called electrons. Recommendations for radiation therapy delivery depend on the type and stage of the cancer.

Targeted therapy: Targeted therapy drugs are used to attack specific parts of lymphoma cells or to increase the immune system’s response to them. These drugs may work in situations where chemotherapy does not.

Corticosteroids: These drugs are made up of cortisol, a naturally-occurring hormone that may affect immune cells such as lymphocytes. Corticosteroids may be taken as pills and injections, or applied directly to the skin in the form of ointments, gels and creams. They also may be injected directly into skin lesions. When applied to the skin, less of the drug is absorbed, resulting in fewer side effects. Long-term use of topical corticosteroids may cause the skin in that area to thin out.

Immunotherapy: Immune therapy drugs used to treat skin lymphomas are designed to help destroy lesions. The drug is most often delivered in the form of a cream. When applied to skin lesions, the drug is designed to activate the immune system to destroy cancer cells.

Most people have twisted an ankle at some point in their life. But if your ankle gets swollen and painful after you twist it, you have most likely sprained it. This means you have stretched and possibly torn the ligaments in your ankle.

Even though ankle sprains are common, they are not always minor injuries. Some people with repeated or severe sprains can develop long-term joint pain and weakness. Treating a sprained ankle can help prevent ongoing ankle problems.

Most types of ankle sprains happen when you make a rapid shifting movement with your foot planted, such as when you play soccer or get tackled in football. Often the ankle rolls outward and the foot turns inward. This causes the ligaments on the outside of the ankle to stretch and tear. Less often, the ankle rolls inward and the foot turns outward. This damages the ligaments on the inside of the ankle.

An ankle sprain can range from mild to severe, depending on how badly the ligament is damaged and how many ligaments are injured. With a mild sprain, the ankle may be tender, swollen, and stiff. But it usually feels stable, and you can walk with little pain. A more serious sprain might include bruising and tenderness around the ankle, and walking is painful. In a severe ankle sprain, the ankle is unstable and may feel “wobbly.” You can’t walk, because the ankle gives out and may be very painful.

With most sprains, you feel pain right away at the site of the tear. Often the ankle starts to swell immediately and may bruise . The ankle area is usually tender to touch, and it hurts to move it.

In more severe sprains, you may hear and/or feel something tear, along with a pop or snap. You will probably have extreme pain at first and will not be able to walk or even put weight on your foot. Usually, the more pain and swelling you have, the more severe your ankle sprain is and the longer it will take to heal.

Treatments:

Initial treatment for an ankle sprain is summarized as the RICE approach:

• Rest. You may need to use crutches until walking is not painful without them.
• Ice. For the first 48 to 72 hours or until swelling goes down, apply an ice pack for 10 to 20 minutes every 1 to 2 hours during the day. After 48 hours, you can continue with ice or try contrast baths. There is not good scientific evidence that ice or contrast baths help, but they are often used.
• Compression. An elastic compression wrap will help decrease swelling and should be worn for the first 24 to 36 hours. A protective brace should also be worn if you try to bear weight on your injured ankle. Don’t apply the wrap too tightly. Loosen the bandage if it gets too tight. Signs that the bandage is too tight include numbness, tingling, increased pain, coolness, or swelling in the area below the bandage. See instructions on how to wrap an ankle  with an elastic bandage. Compression wraps do not offer protection, except by reminding you to be careful of your ankle.

  Sprained Ankle: Using a Compression Wrap

• Elevation. Raise your ankle above the level of your heart for 2 to 3 hours a day if possible to decrease swelling and bruising.

If you are not taking any prescription pain relievers, you may want to take an over-the-counter pain reliever such as ibuprofen or naproxen to reduce pain and swelling. Be safe with medicines. Read and follow all instructions on the label.

It may help to wear hiking boots or other high-top, lace-up shoes for support. But use caution. Don’t force your foot into a boot if you feel a lot of pain or discomfort.

The pancreas is a large gland behind the stomach and next to the small intestine. The pancreas does two main things:

1. It releases powerful digestive enzymes into the small intestine to aid the digestion of food.
2. It releases the hormones insulin and glucagon into the bloodstream. These hormones help the body control how it uses food for energy.

Pancreatitis is a disease in which the pancreas becomes inflamed. Pancreatic damage happens when the digestive enzymes are activated before they are released into the small intestine and begin attacking the pancreas.

There are two forms of pancreatitis: acute and chronic.

Acute pancreatitis. Acute pancreatitis is a sudden inflammation that lasts for a short time. It may range from mild discomfort to a severe, life-threatening illness. Most people with acute pancreatitis recover completely after getting the right treatment. In severe cases, acute pancreatitis can result in bleeding into the gland, serious tissue damage, infection, and cystformation. Severe pancreatitis can also harm other vital organs such as the heart, lungs, and kidneys.

Chronic pancreatitis. Chronic pancreatitis is long-lasting inflammationof the pancreas. It most often happens after an episode of acute pancreatitis. Heavy alcohol drinking is another big cause. Damage to the pancreas from heavy alcohol use may not cause symptoms for many years, but then the person may suddenly develop severe pancreatitis symptoms.

Symptoms of acute pancreatitis:

• Upper abdominal pain that radiates into the back; it may be aggravated by eating, especially foods high in fat.
• Swollen and tender abdomen
• Nausea and vomiting
• Fever
• Increased heart rate

The symptoms of chronic pancreatitis are similar to those of acute pancreatitis. Patients frequently feel constant pain in the upper abdomen that radiates to the back. In some patients, the pain may be disabling. Other symptoms are weight loss caused by poor absorption (malabsorption) of food. This malabsorption happens because the gland is not releasing enough enzymes to break down food. Also, diabetes may develop if the insulin-producing cells of the pancreas are damaged.

In most cases, acute pancreatitis is caused by gallstones or heavy alcohol use. Other causes include medications, infections, trauma, metabolic disorders, and surgery. In up to 15% of people with acute pancreatitis, the cause is unknown.

In about 70% of people, chronic pancreatitis is caused by long-time alcohol use. Other causes include gallstones, hereditary disorders of the pancreas, cystic fibrosis, high triglycerides, and certain medicines. In about 20% to 30% of cases, the cause of chronic pancreatitis is unknown.

Pancreatitis can happen to anyone, but it is more common in people with certain risk factors.

Risk factors of acute pancreatitis include:

• Gallstones
• Heavy alcohol drinking

Acute pancreatitis may be the first sign of gallstones. Gallstones can block the pancreatic duct, which can cause acute pancreatitis.

Risk factors for chronic pancreatitis include:

• Heavy alcohol drinking for a long time
• Certain hereditary conditions, such as cystic fibrosis
• Gallstones
• Conditions such as high triglycerides and lupus

People with chronic pancreatitis are usually men between ages 30 and 40, but chronic pancreatitis also may occur in women.

To diagnose acute pancreatitis, doctors measure levels in the blood of two digestive enzymes, amylase and lipase. High levels of these two enzymes strongly suggest acute pancreatitis.

Doctors may also use other tests, such as:

• Pancreatic function test to find out if the pancreas is making the right amounts of digestive enzymes
• Glucose tolerance test to measure damage to the cells in the pancreas that make insulin
• Ultrasound, CT scan, and MRI, which make images of the pancreas so that problems may be seen
• ERCP to look at the pancreatic and bile ducts using X-rays
• Biopsy, in which a needle is inserted into the pancreas to remove a small tissue sample for study

Treatment for acute pancreatitis

People with acute pancreatitis are typically treated with IV fluids and pain medications in the hospital. In some patients, the pancreatitis can be severe and they may need to be admitted to an intensive care unit (ICU). In the ICU, the patient is closely watched because pancreatitis can damage the heart, lungs, or kidneys. Some cases of severe pancreatitis can result in death of pancreatic tissue. In these cases, surgery may be necessary to remove the dead or damaged tissue if an infection develops.

An acute attack of pancreatitis usually lasts a few days. An acute attack of pancreatitis caused by gallstones may require removal of the gallbladder or surgery of the bile duct. After the gallstones are removed and the inflammation goes away, the pancreas usually returns to normal.

Treatment for chronic pancreatitis

Chronic pancreatitis can be difficult to treat. Doctors will try to relieve the patient’s pain and improve the nutritionproblems. Patients are generally given pancreatic enzymes and may need insulin. A low-fat diet may also help.

Serous cystadenoma of pancreas is a benign tumor of pancreas. This cystic neoplasm is made up of several small cysts spread into a honeycomb like appearance. Serous cystadenoma of pancreas is mainly present in women, especially over the age of 60 years. The size of tumor is usually small. This type of cystic neoplasm of pancreas does not produce any signs and symptoms in majority of cases.

If symptoms occur, they are abdominal pain, loss of appetite, and indigestion.

In many patients this tumor is an incidental finding. It is detected accidentally when the patient undergoes radiological tests for some other medical condition. The neoplasm generally is located in body or tail of pancreas. Pancreatic gland is divided into head, body and tail.

Serous cystadenoma of pancreas is a benign tumor.

It does not transform into malignant cancer. Usually no treatment is necessary, unless it gets enlarge in size. In such case the tumor may need surgical removal.

Causes Of Pancreatic Serous Cystadenoma

Pancreas is an important gland which produces digestive juices as well as insulin and glucagon hormone needed for maintaining optimum level of sugar in the blood. Pancreas is an abdominal organ. Serous cystadenoma of pancreas is an uncommon form of cystic tumor of pancreas.

The exact cause is yet not completely understood. It accounts for approximately 1% of all types of pancreatic tumor. Both males and females can be affected with this tumor; however, there is a strong predilection for females. It usually occurs in people over the age of 60 years.

The particular risk factors for development of serous cystadenoma of pancreas is not known, but common risk factors that attribute development of any pancreatic tumor are also suspected to be the cause. This includes elderly age, cigarette smoking, alcoholism, obesity, poorly controlled diabetes, chronic pancreatitis, exposure to environmental pollutants, and cirrhosis of liver.

Signs And Symptoms Of Serous Cystadenoma Of Pancreas

The signs and symptoms of serous cystadenoma of pancreas depend on its size. Almost one third of patients suffering from this condition do not reveal any symptoms. In majority of cases the size is very small typically less than 10mm. It is a solitary tumor with network of several tiny cysts that gives a morphological appearance of honeycomb. The serous cyst is present in either tail or body of pancreas.

If the serous cystadenoma of pancreas enlarges in its size, it can give rise to following symptoms;

• Unwarranted loss of weight.
• Pain in middle of back, exactly just below the space between two scapula.
• Pain in abdomen
• Loss of appetite
• Indigestion
• Nausea and vomiting
• A large tumor can cause obstruction in flow of bile and enzymatic juices. This may result in jaundice or yellow discoloration of eyes, skin and nail.
• When jaundice is present the color of urine becomes dark yellow.
• There may be black tarry stool. In medical terminology it is referred as malena.

Serous cystadenoma of pancreas is well demarcated tumor. It mostly occurs as a single entity. Its size may be less than 10mm. But the tumor has potential to enlarge in size.

Serous Cystadenoma Of Pancreas Complications

Normally there are no complications associated with serous cystadenoma of pancreas. However, when they occur it is because of its enlarged size. Complications may not be life threatening but often cause extreme discomfort to the patient.

• A large tumor can cause obstruction in gastric and intestinal motility.
• It can cause obstruction in the pathway of biliary tract resulting in jaundice.
• A large tumor can cause interference with the organs located nearby pancreas. This may create problems in the functioning of the affected organ.
• If the pancreatic cells are destroyed in large numbers due to enlargement of serous cystadenoma, it may give rise to diabetes.

Treatment Of Serous Cystadenoma Of Pancreas

Pancreatic serous cystadenoma is typically small and benign tumor. A giant serous cystadenoma is a rare event. It is more found in females of elderly age. Most patients remain asymptomatic due to the small size and slow growth. Both these factors do not exert pressure on the adjacent organs and tissues. Hence majority of doctors recommend wait and watch approach to the patients. However, regular follow up is always necessary in such cases.

If there is a giant sized serous cystadenoma of pancreas which adheres or infiltrates the nearby tissues causing symptoms, it may need to be removed through complete surgical excision of the growth. Even after surgical removal of the tumor, patient needs regular check up with the doctor. The prognosis of this condition is good with treatment.