Rheumatoid arthritis (RA) is the most common type of autoimmune arthritis. It is caused when the immune system is not working properly. RA causes pain and swelling in the wrist and small joints of the hand and feet.
Treatments for RA can stop joint pain and swelling. Treatment also prevents joint damage.

These following joint symptoms are clues to RA:

• Joint pain, tenderness, swelling or stiffness for six weeks or longer
•  Morning stiffness for 30 minutes or longer
• More than one joint is affected
• Small joints (wrists, certain joints of the hands and feet) are affected
• The same joints on both sides of the body are affected.

Studies show that people who receive early treatment for RA feel better sooner and more often, and are more likely to lead an active life. They also are less likely to have the type of joint damage that leads to joint replacement.

RA is a complex disease, but many advances in treatment have occurred recently. Rheumatologists are doctors who are experts in diagnosing and treating arthritis and other diseases of the joints, muscles and bones. Thus, they are best qualified to make a proper diagnosis of RA. They can also advise patients about the best treatment options.

to know more details:- send in your queries to query@gtsmeditour.com or WhatsApp your latest medical reports to +91-9880149003

Stomach cancer is the fourth leading cause of cancer-related deaths worldwide. In India too, stomach cancer claims thousands of lives, with a higher number of cases reported in the southern states. Its symptoms are not recognized until it reaches an advanced stage, leading to late diagnosis.

Symptoms:

• Discomfort or pain in the stomach area
• Nausea and vomiting
• Difficulty swallowing
• Weight loss
• Vomiting blood or blood in the stool
• Feeling full or bloated after a small meal

Treatments:

In stomach cancer, the degree of extent of disease is the most important factor that influences choice of treatment. This is where staging assessment becomes critical. Staging of stomach cancer is based on whether the cancer is localized to the stomach or has spread to the lymph nodes or other parts of the body.

Surgery remains the mainstay of treatment for stomach cancer, both globally and in India especially when the cancer is detected in its early stages and limited to the inner lining of the stomach. Treatment of advanced stages of stomach cancer includes chemotherapy and targeted therapy.

 

The good news is that treatment for stomach cancer has evolved over the last decade. These advancements have helped to  improve treatment outcomes and increase patient survival.

To know more details:- send in your queries to query@gtsmeditour.com or WhatsApp your latest medical reports to +91-9880149003.

Stem cells have tremendous promise to help us understand and treat a range of diseases, injuries and other health-related conditions. Their potential is evident in the use of blood stem cells to treat diseases of the blood, a therapy that has saved the lives of thousands of children with leukemia; and can be seen in the use of stem cells for tissue grafts to treat diseases or injury to the bone, skin and surface of the eye. Important clinical trials involving stem cells are underway for many other conditions and researchers continue to explore new avenues using stem cells in medicine.

There is still a lot to learn about stem cells, however, and their current applications as treatments are sometimes exaggerated by the media and other parties who do not fully understand the science and current limitations, and also by “clinics” looking to capitalize on the hype by selling treatments to chronically ill or seriously injured patients. The information on this page is intended to help you understand both the potential and the limitations of stem cells at this point in time, and to help you spot some of the misinformation that is widely circulated by clinics offering unproven treatments.

Stem cell researchers are making great advances in understanding normal development, figuring out what goes wrong in disease and developing and testing potential treatments to help patients. They still have much to learn, however, about how stem cells work in the body and their capacity for healing. Safe and effective treatments for most diseases, conditions and injuries are in the future.

Retinal detachment describes an emergency situation in which a thin layer of tissue (the retina) at the back of the eye pulls away from its normal position.

Retinal detachment separates the retinal cells from the layer of blood vessels that provides oxygen and nourishment. The longer retinal detachment goes untreated, the greater your risk of permanent vision loss in the affected eye.

Warning signs of retinal detachment may include one or all of the following: the sudden appearance of floaters and flashes and reduced vision. Contacting an eye specialist (ophthalmologist) right away can help save your vision.

Symptoms

Retinal detachment itself is painless. But warning signs almost always appear before it occurs or has advanced, such as:

• The sudden appearance of many floaters — tiny specks that seem to drift through your field of vision
• Flashes of light in one or both eyes (photopsia)
• Blurred vision
• Gradually reduced side (peripheral) vision
• A curtain-like shadow over your visual field

When to see a doctor

Seek immediate medical attention if you are experiencing the signs or symptoms of retinal detachment. Retinal detachment is a medical emergency in which you can permanently lose your vision.

Causes

There are three different types of retinal detachment:

• Rhegmatogenous (reg-ma-TODGE-uh-nus). These types of retinal detachments are the most common. Rhegmatogenous detachments are caused by a hole or tear in the retina that allows fluid to pass through and collect underneath the retina, pulling the retina away from underlying tissues. The areas where the retina detaches lose their blood supply and stop working, causing you to lose vision.The most common cause of rhegmatogenous detachment is aging. As you age, the gel-like material that fills the inside of your eye, known as the vitreous (VIT-ree-us), may change in consistency and shrink or become more liquid. Normally, the vitreous separates from the surface of the retina without any complications — a common condition called posterior vitreous detachment (PVD). One complication of this separation is a tear.As the vitreous separates or peels off the retina, it may tug on the retina with enough force to create a retinal tear. Left untreated, the liquid vitreous can pass through the tear into the space behind the retina, causing the retina to become detached.
• Tractional. This type of detachment can occur when scar tissue grows on the retina’s surface, causing the retina to pull away from the back of the eye. Tractional detachment is typically seen in people who have poorly controlled diabetes or other conditions.
• Exudative. In this type of detachment, fluid accumulates beneath the retina, but there are no holes or tears in the retina. Exudative detachment can be caused by age-related macular degeneration, injury to the eye, tumors or inflammatory disorders.

Diagnosis

Your doctor may use the following tests, instruments and procedures to diagnose retinal detachment:

• Retinal examination. The doctor may use an instrument with a bright light and special lenses to examine the back of your eye, including the retina. This type of device provides a highly detailed view of your whole eye, allowing the doctor to see any retinal holes, tears or detachments.
• Ultrasound imaging. Your doctor may use this test if bleeding has occurred in the eye, making it difficult to see your retina.

Your doctor will likely examine both eyes even if you have symptoms in just one. If a tear is not identified at this visit, your doctor may ask you to return within a few weeks to confirm that your eye has not developed a delayed tear as a result of the same vitreous separation. Also, if you experience new symptoms, it’s important to return to your doctor right away.

Treatment

Surgery is almost always used to repair a retinal tear, hole or detachment. Various techniques are available. Ask your ophthalmologist about the risks and benefits of your treatment options. Together you can determine what procedure or combination of procedures is best for you.

Retinal tears

When a retinal tear or hole hasn’t yet progressed to detachment, your eye surgeon may suggest one of the following procedures to prevent retinal detachment and preserve vision.

• Laser surgery (photocoagulation). The surgeon directs a laser beam into the eye through the pupil. The laser makes burns around the retinal tear, creating scarring that usually “welds” the retina to underlying tissue.
• Freezing (cryopexy). After giving you a local anesthetic to numb your eye, the surgeon applies a freezing probe to the outer surface of the eye directly over the tear. The freezing causes a scar that helps secure the retina to the eye wall.

Both of these procedures are done on an outpatient basis. After your procedure, you’ll likely be advised to avoid activities that might jar the eyes — such as running — for a couple of weeks or so

If your retina has detached, you’ll need surgery to repair it, preferably within days of a diagnosis. The type of surgery your surgeon recommends will depend on several factors, including how severe the detachment is.

• Injecting air or gas into your eye. In this procedure, called pneumatic retinopexy (RET-ih-no-pek-see), the surgeon injects a bubble of air or gas into the center part of the eye (the vitreous cavity). If positioned properly, the bubble pushes the area of the retina containing the hole or holes against the wall of the eye, stopping the flow of fluid into the space behind the retina. Your doctor also uses cryopexy during the procedure to repair the retinal break.Fluid that had collected under the retina is absorbed by itself, and the retina can then adhere to the wall of your eye. You may need to hold your head in a certain position for up to several days to keep the bubble in the proper position. The bubble eventually will reabsorb on its own.
• Indenting the surface of your eye. This procedure, called scleral (SKLAIR-ul) buckling, involves the surgeon sewing (suturing) a piece of silicone material to the white of your eye (sclera) over the affected area. This procedure indents the wall of the eye and relieves some of the force caused by the vitreous tugging on the retina.If you have several tears or holes or an extensive detachment, your surgeon may create a scleral buckle that encircles your entire eye like a belt. The buckle is placed in a way that doesn’t block your vision, and it usually remains in place permanently.
• Draining and replacing the fluid in the eye. In this procedure, called vitrectomy (vih-TREK-tuh-me), the surgeon removes the vitreous along with any tissue that is tugging on the retina. Air, gas or silicone oil is then injected into the vitreous space to help flatten the retina.Eventually the air, gas or liquid will be absorbed, and the vitreous space will refill with body fluid. If silicone oil was used, it may be surgically removed months later.Vitrectomy may be combined with a scleral buckling procedure.

Risk factors

The following factors increase your risk of retinal detachment:

• Aging — retinal detachment is more common in people over age 50
• Previous retinal detachment in one eye
• Family history of retinal detachment
• Extreme nearsightedness (myopia)
• Previous eye surgery, such as cataract removal
• Previous severe eye injury
• Previous other eye disease or disorder, including retinoschisis, uveitis or thinning of the peripheral retina (lattice degeneration)

Bariatric Surgery Procedures

Many things can leave your skin dry and flaky, from cold air to the chlorine in swimming pools. In a small number of people, a group of diseases called ichthyosis causes skin dryness and scaling.It can’t be cured, but treatments can relieve the scaling and make you feel more comfortable in your own skin.Ichthyosis is not one disease, but a family of about 20 skin conditions that lead to dry skin. People with this condition lose the protective barrier that keeps moisture in their skin. They also make new skin cells too quickly or shed old cells too slowly. This leads to a buildup of thick, scaly skin.The condition gets its name from the Greek word for fish, because the skin looks like fish scales.

Types of Ichthyosis

Some types only cause dry and scaly skin. Others cause problems inside the body, too.

Most forms of the disease are very rare. The two least rare types are:

• Ichthyosis vulgaris. It affects about 1 out of every 250 people.
• X-linked recessive ichthyosis. It affects about 1 out of 6,000 people, but only males.

What Causes Ichthyosis?

It can be inherited or acquired.

Inherited ichthyosis: This is caused by mutations, or changes, to genes.

Genes are the codes that tell your body to make proteins, which determine how your body looks and functions.

Ichthyosis gene mutations affect that proteins that protect your skin and keep it moist. They also affect how quickly skin cells multiply or are shed.

Parents pass these genes to their children. Sometimes children whose parents don’t have ichthyosis get the disease before birth. The gene change happens inside the egg or sperm — or when the egg and sperm meet to make a baby. These are called “spontaneous mutations.”

Some people have the gene mutation but don’t show symptoms. They are called carriers.

Acquired ichthyosis: This starts in adulthood. Doctors don’t know what causes it.

People with the acquired form often have other conditions, such as:

• Underactive thyroid gland
• Kidney disease
• Sarcoidosis, a rare disease that causes patches of inflammation inside the body
• Cancer such as Hodgkin lymphoma
• HIV infection

Some medicines might also trigger the condition:

• Cancer drugs such as vemurafenib (Zelboraf), hydroxyurea (Hydrea, Droxia), and protease inhibitors (a class of drugs used to treat HIVinfections)
• Nicotinic acid, which is used to treat high cholesterol

Symptoms

In the inherited forms, symptoms appear at birth or in the first few months of life.

Dry, scaly skin is the main symptom. The scales form on only some parts of the body, such as the:

• Trunk
• Stomach
• Buttocks
• Legs
• Face and scalp

The scales can be white, gray, or dark brown. They might have thick or thin cracks running through them.

Dryness and scaling get worse in cold, dry weather. They usually improve in warmer weather.

Other signs of ichthyosis are:

• Skin redness
• Blisters
• Peeling
• Itchiness
• Pain
• Lines on the palms of the hands and soles of the feet
• Tight skin that makes it hard to move

Many people with ichthyosis also have eczema, a red, itchy rash.

Complications

Skin is your body’s barrier. It holds moisture inside and keeps out bacteria and other invaders that might make you sick. When ichthyosis makes pieces of your skin scale off, you lose some of this protective layer.

Scaling can lead to complications such as:

• Infections
• Dehydration
• Blocked sweat glands, which can lead to overheating
• Slow hair growth from scales on the scalp
• Burning more calories, because the skin has to work harder to turn over cells

Ichthyosis can cause emotional issues, too. The scales can affect the way you look. People with this condition sometimes feel depressed and have low self-esteem.

Men with ichthyosis are also at increased risk for:

• Testicular cancer
• Undescended or hidden testicles
• Low sperm count

Other complications include:

• Vision loss from damage to the cornea (the clear layer in the front of the eye)
• Brain and nervous system problems

Diagnosis

Sometimes it’s so mild that it looks like regular dry skin. If the dryness and scaling bother you, see a dermatologist, a doctor who treats skin problems, for treatment.

She might take a sample of skin to check under a microscope. This is called a biopsy.

She might also test your saliva for gene changes that cause certain types of ichthyosis.

Treatments

It can’t be cured, but treatments can help you manage dry and scaly skin.

Rub cream, lotion, or ointment onto your skin every day to add moisture. Look for rich creams that have any of these ingredients: lanolin, alpha hydroxy acids, urea, or propylene glycol. Products with ceramides or cholesterol also keep skin moist.

Apply the lotion right after you step out of the shower or bath, when your skin is still damp. This will help hold in moisture. Other things you can try:

• Take baths in salt water.
• Rub your skin with a pumice stone.
• Remove dead skin with a product that contains salicylic acid, glycolic acid, or lactic acid.

If the dryness and scaling are severe, your doctor might prescribe an oral retinoid medicine such as acitretin (Soriatane) or isotretinoin (Absorica, Claravis, Sotret, and others). Retinoids can cause side effects such as weakened bones, dry mouth, and upset stomach.

Ichthyosis isn’t life-threatening, but it can be life-changing.

Your dermatologist can recommend treatments to help your skin look and feel better. If you feel depressed or have low self-esteem, talk to a therapist or other mental health experts.

Childhood ependymoma is a type of brain tumor. A tumor begins when healthy cells change and grow out of control, forming a mass. A tumor can be cancerous or benign. A cancerous tumor is malignant, meaning it can grow and spread to other parts of the body. A benign tumor means the tumor can grow but will not spread. Ependymoma is a rare, cancerous brain tumor.

Ependymoma starts from radial glial cells, which are a type of cell in the brain. Even though ependymoma can occur in any part of the brain or spine, it most commonly occurs in the cerebellum. The cerebellum is the part of the brain that coordinates the body’s actions.

Symptoms & Causes:

Children with ependymoma may experience the following symptoms or signs. Sometimes, children with ependymoma do not have any of these changes. Or, the cause of a symptom may be another medical condition that is not a tumor.

• Headaches
• Nausea and vomiting
• Changes in vision, such as blurriness
• Difficulty with walking or balance
• Jerky eye movements
• Neck pain
• Reaching childhood developmental milestones more slowly than expected
• Seizures/convulsions, which are sudden involuntary movements of a person’s muscles

If you are concerned about any changes your child experiences, please talk with your child’s doctor. Your doctor will ask how long and how often your child has been experiencing the symptom(s), in addition to other questions. This is to help find out the cause of the problem, called a diagnosis.

If a brain tumor is diagnosed, relieving symptoms remains an important part of care and treatment. This may also be called symptom management, palliative care, or supportive care. Be sure to talk with your child’s health care team about symptoms your child experiences, including any new symptoms or a change in symptoms.

Treatments:

option: 1-surgery

or

2- Chemotherapy

or

3- Radiation

 

Parkinson’s disease is a progressive nervous system disorder that affects movement. Symptoms start gradually, sometimes starting with a barely noticeable tremor in just one hand. Tremors are common, but the disorder also commonly causes stiffness or slowing of movement.

In the early stages of Parkinson’s disease, your face may show little or no expression. Your arms may not swing when you walk. Your speech may become soft or slurred. Parkinson’s disease symptoms worsen as your condition progresses over time.

Although Parkinson’s disease can’t be cured, medications might significantly improve your symptoms. Occasionally, your doctor may suggest surgery to regulate certain regions of your brain and improve your symptoms.

 

 

Symptoms

Parkinson’s disease signs and symptoms can be different for everyone. Early signs may be mild and go unnoticed. Symptoms often begin on one side of your body and usually remain worse on that side, even after symptoms begin to affect both sides.

Parkinson’s signs and symptoms may include:

• Tremor. A tremor, or shaking, usually begins in a limb, often your hand or fingers. You may a rub your thumb and forefinger back-and-forth, known as a pill-rolling tremor. Your hand may tremor when it’s at rest.
• Slowed movement (bradykinesia). Over time, Parkinson’s disease may slow your movement, making simple tasks difficult and time-consuming. Your steps may become shorter when you walk. It may be difficult to get out of a chair. You may drag your feet as you try to walk.
• Rigid muscles. Muscle stiffness may occur in any part of your body. The stiff muscles can be painful and limit your range of motion.
• Impaired posture and balance. Your posture may become stooped, or you may have balance problems as a result of Parkinson’s disease.
• Loss of automatic movements. You may have a decreased ability to perform unconscious movements, including blinking, smiling or swinging your arms when you walk.
• Speech changes. You may speak softly, quickly, slur or hesitate before talking. Your speech may be more of a monotone rather than with the usual inflections.
• Writing changes. It may become hard to write, and your writing may appear small.

Causes

In Parkinson’s disease, certain nerve cells (neurons) in the brain gradually break down or die. Many of the symptoms are due to a loss of neurons that produce a chemical messenger in your brain called dopamine. When dopamine levels decrease, it causes abnormal brain activity, leading to symptoms of Parkinson’s disease.

The cause of Parkinson’s disease is unknown, but several factors appear to play a role, including:

• Your genes. Researchers have identified specific genetic mutations that can cause Parkinson’s disease. But these are uncommon except in rare cases with many family members affected by Parkinson’s disease.However, certain gene variations appear to increase the risk of Parkinson’s disease but with a relatively small risk of Parkinson’s disease for each of these genetic markers.
• Environmental triggers. Exposure to certain toxins or environmental factors may increase the risk of later Parkinson’s disease, but the risk is relatively small.

Researchers have also noted that many changes occur in the brains of people with Parkinson’s disease, although it’s not clear why these changes occur. These changes include:

• The presence of Lewy bodies. Clumps of specific substances within brain cells are microscopic markers of Parkinson’s disease. These are called Lewy bodies, and researchers believe these Lewy bodies hold an important clue to the cause of Parkinson’s disease.
• Alpha-synuclein is found within Lewy bodies. Although many substances are found within Lewy bodies, scientists believe an important one is the natural and widespread protein called alpha-synuclein (a-synuclein). It’s found in all Lewy bodies in a clumped form that cells can’t break down. This is currently an important focus among Parkinson’s disease researchers.

Risk factors

Risk factors for Parkinson’s disease include:

• Age. Young adults rarely experience Parkinson’s disease. It ordinarily begins in middle or late life, and the risk increases with age. People usually develop the disease around age 60 or older.
• Heredity. Having a close relative with Parkinson’s disease increases the chances that you’ll develop the disease. However, your risks are still small unless you have many relatives in your family with Parkinson’s disease.
• Sex. Men are more likely to develop Parkinson’s disease than are women.
• Exposure to toxins. Ongoing exposure to herbicides and pesticides may slightly increase your risk of Parkinson’s disease.

Complications

Parkinson’s disease is often accompanied by these additional problems, which may be treatable:

• Thinking difficulties. You may experience cognitive problems (dementia) and thinking difficulties. These usually occur in the later stages of Parkinson’s disease. Such cognitive problems aren’t very responsive to medications.
• Depression and emotional changes. You may experience depression, sometimes in the very early stages. Receiving treatment for depression can make it easier to handle the other challenges of Parkinson’s disease.You may also experience other emotional changes, such as fear, anxiety or loss of motivation. Doctors may give you medications to treat these symptoms.
• Swallowing problems. You may develop difficulties with swallowing as your condition progresses. Saliva may accumulate in your mouth due to slowed swallowing, leading to drooling.
• Chewing and eating problems. Late-stage Parkinson’s disease affects the muscles in your mouth, making chewing difficult. This can lead to choking and poor nutrition.
• Sleep problems and sleep disorders. People with Parkinson’s disease often have sleep problems, including waking up frequently throughout the night, waking up early or falling asleep during the day.People may also experience rapid eye movement sleep behavior disorder, which involves acting out your dreams. Medications may help your sleep problems.
• Bladder problems. Parkinson’s disease may cause bladder problems, including being unable to control urine or having difficulty urinating.
• Constipation. Many people with Parkinson’s disease develop constipation, mainly due to a slower digestive tract.

You may also experience:

• Blood pressure changes. You may feel dizzy or lightheaded when you stand due to a sudden drop in blood pressure (orthostatic hypotension).
• Smell dysfunction. You may experience problems with your sense of smell. You may have difficulty identifying certain odors or the difference between odors.
• Fatigue. Many people with Parkinson’s disease lose energy and experience fatigue, especially later in the day. The cause isn’t always known.
• Pain. Some people with Parkinson’s disease experience pain, either in specific areas of their bodies or throughout their bodies.
• Sexual dysfunction. Some people with Parkinson’s disease notice a decrease in sexual desire or performance.

Prevention

Because the cause of Parkinson’s is unknown, proven ways to prevent the disease also remain a mystery.

Some research has shown that regular aerobic exercise might reduce the risk of Parkinson’s disease.

Some other research has shown that people who drink caffeine — which is found in coffee, tea and cola — get Parkinson’s disease less often than those who don’t drink it. However, it is still not known whether caffeine actually protects against getting Parkinson’s, or is related in some other way. Currently there is not enough evidence to suggest drinking caffeinated beverages to protect against Parkinson’s. Green tea is also related to a reduced risk of developing Parkinson’s disease.