Global Treatment Services Pvt. Ltd.

Global Treatment Services

Esophageal Cancer : Causes, Symptoms & Treatments

What Is Esophageal Cancer?

The esophagus is a muscular tube that’s responsible for moving food from the throat to the stomach. Esophageal cancer can occur when a malignant tumor forms in the lining of the esophagus. As the tumor grows, it can affect the deep tissues and muscle of the esophagus. A tumor can appear anywhere along the length of the esophagus, including the junction of the esophagus and stomach, or where the two meet.

What Are the Common Types of Esophageal Cancer?
 There are two common types of esophageal cancer.

Squamous cell carcinoma occurs when cancer starts in the flat, thin cells that make up the lining of the esophagus. This form most often appears in the top or middle of the esophagus, but it can appear anywhere.

Adenocarcinoma occurs when cancer starts in the glandular cells of the esophagus that are responsible for the production of fluids such as mucus. Adenocarcinomas are most common in the lower portion of the esophagus.

 What Are the Symptoms of Esophageal Cancer?

During the early stages of esophageal cancer, you probably won’t experience any symptoms. As your cancer progresses, you may experience:

  • unintentional weight loss
  • indigestion
  • heartburn
  • difficulty or painful swallowing
  • frequent choking while eating
  • vomiting
  • food coming back up the esophagus
  • chest pain
  • fatigue

What Causes Esophageal Cancer?

As with most cancers, the cause of esophageal cancer isn’t yet known. It’s believed to be related to abnormalities, or mutations, in the DNA of the cells related to the esophagus. These mutations signal the cells to multiply more rapidly than normal cells. These mutations also disrupt the signal for these cells to die when they should. This causes them to accumulate and become tumors.

Who Is at Risk for Developing Esophageal Cancer?

Experts believe that the irritation of esophagus cells contributes to the development of cancer. Some habits and conditions that can cause irritation include:
  • consuming alcohol
  • smoking
  • having a reflux disorder, such as gastroesophageal reflux disease (GERD)
  • being overweight
  • not eating enough fruits and vegetables
  • having Barrett’s esophagus, which is a condition characterized by damaged esophageal lining due to GERD

People at increased risk of esophageal cancer include the following:

  • Men are three times as likely to develop esophageal cancer as women.
  • Esophageal cancer is more common in African-Americans than in other races.
  • Your chances of developing esophageal cancer increase with age. If you’re over the age of 45, your risk may be higher.

Treating Esophageal Cancer

Your doctor may recommend surgery if the cancer hasn’t spread to other parts of your body. Your doctor may instead recommend chemotherapy or radiation therapy as the best course of action. These treatments are also sometimes done to shrink tumors in the esophagus so that they can be removed more easily with surgery.

Surgery

If the cancer hasn’t grown past the superficial layers of the esophagus, your doctor can remove the tumor using an endoscope. In more serious cases, a portion of the esophagus and sometimes the lymph nodes around it are removed. The tube is reconstructed with tissue from the stomach or large intestine. In severe cases, a portion of the top of the stomach may be removed as well.

The risks of surgery can include bleeding, leaking in the area where the rebuilt esophagus was attached to the stomach, and infection.

Chemotherapy

Chemotherapy involves the use of drugs to attack cancer cells. Chemotherapy may be used before or after surgery. It sometimes accompanies the use of radiation therapy.

Chemotherapy does have several side effects. Most are related to the fact that the drugs used also kill healthy cells. Your side effects will vary depending on the drugs your doctor uses. These side effects can include:

  • hair loss
  • nausea
  • vomiting
  • fatigue
  • pain
  • neuropathy

Radiation Therapy

Radiation therapy uses beams of radiation to kill cancer cells. Radiation may be administered externally with the use of a machine or internally with a device placed near the tumor, which is called brachytherapy. Radiation is commonly used along with chemotherapy and side effects are usually more severe when combined treatment is used. The side effects of radiation can include:

  • skin that looks sunburned
  • pain or difficulty when swallowing
  • fatigue
  • painful ulcers in the lining of the esophagus

It’s possible to experience some side effects of treatment long after treatment finishes. These can include esophageal stricture, where the tissue becomes less flexible and can cause the esophagus to narrow, making it painful or difficult to swallow.

Other Treatments

If your esophagus is obstructed as a result of cancer, your doctor may be able to implant a stent, or tube made of metal, into your esophagus to keep it open.

They may also be able to use photodynamic therapy, which involves injecting the tumor with a photosensitive drug that attacks the tumor when exposed to light.

 

Pancreatic Cancer : Causes, symptoms & Treatments

Signs and symptoms of pancreatic cancer:

The symptoms of exocrine pancreatic cancers and pancreatic neuroendocrine tumors (NETs) are often different, so they are described separately.

Having one or more of the symptoms below does not mean you have pancreatic cancer. In fact, many of these symptoms are more likely to be caused by other conditions. Still, if you have any of these symptoms, it’s important to have them checked by a doctor so that the cause can be found and treated, if needed.

Signs and symptoms of exocrine pancreatic cancer:

Early pancreatic cancers often do not cause any signs or symptoms. By the time they do cause symptoms, they have often already spread outside the pancreas.

Jaundice and related symptoms

Jaundice is yellowing of the eyes and skin. Most people with pancreatic cancer (and virtually all people with ampullary cancer) will have jaundice as one of their first symptoms.

Jaundice is caused by the buildup of bilirubin, a dark yellow-brown substance made in the liver. Normally, the liver excretes bilirubin as part of a liquid called bile. Bile goes through the common bile duct into the intestines, where it helps break down fats. It eventually leaves the body in the stool. When the common bile duct becomes blocked, bile can’t reach the intestines, and the level of bilirubin in the body builds up.

Cancers that start in the head of the pancreas are near the common bile duct. These cancers can press on the duct and cause jaundice while they are still fairly small, which can sometimes lead to these tumors being found at an early stage. But cancers that start in the body or tail of the pancreas don’t press on the duct until they have spread through the pancreas. By this time, the cancer has often spread beyond the pancreas as well.

When pancreatic cancer spreads, it often goes to the liver. This can also lead to jaundice.

Dark urine: Sometimes, the first sign of jaundice is darker urine. As bilirubin levels in the blood increase, the urine becomes brown in color.

Light-colored or greasy stools: Bilirubin normally helps give stools their brown color. If the bile duct is blocked, stools might be pale or gray. Also, if bile and pancreatic enzymes can’t get through to the intestines to help break down fats, the stools can become greasy and might float in the toilet.

Itchy skin: When bilirubin builds up in the skin, it can start to itch as well as turning yellow.

Pancreatic cancer is not the most common cause of jaundice. Other causes, such as gallstones, hepatitis, and other liver and bile duct diseases, are much more common.

Belly or back pain

Pain in the abdomen (belly) or back is common in pancreatic cancer. Cancers that start in the body or tail of the pancreas can grow fairly large and start to press on other nearby organs, causing pain. The cancer may also spread to the nerves surrounding the pancreas, which often causes back pain. Of course, pain in the abdomen or back is fairly common and is most often caused by something other than pancreatic cancer.

Weight loss and poor appetite

Unintended weight loss is very common in people with pancreatic cancer. These people often have little or no appetite.

Nausea and vomiting

If the cancer presses on the far end of the stomach it can partly block it, making it hard for food to get through. This can cause nausea, vomiting, and pain that tend to be worse after eating.

Gallbladder or liver enlargement

If the cancer blocks the bile duct, bile can build up in the gallbladder, making it larger. Sometimes a doctor can feel this (as a large lump under the right ribcage) during a physical exam. It can also be seen on imaging tests.

Pancreatic cancer can also sometimes enlarge the liver, especially if the cancer has spread to the liver. The doctor might be able to feel this below the right ribcage as well on an exam, or it might be seen on imaging tests.

Blood clots

Sometimes, the first clue that someone has pancreatic cancer is a blood clot in a large vein, often in the leg. This is called a deep vein thrombosis or DVT. Symptoms can include pain, swelling, redness, and warmth in the affected leg. Sometimes a piece of the clot can break off and travel to the lungs, which might make it hard to breathe or cause chest pain. A blood clot in the lungs is called a pulmonary embolism or PE.

Still, having a blood clot does not usually mean that you have cancer. Most blood clots are caused by other things.

Fatty tissue abnormalities

Some people with pancreatic cancer develop an uneven texture of the fatty tissue underneath the skin. This is caused by the release of the pancreatic enzymes that digest fat.

Diabetes

Rarely, pancreatic cancers cause diabetes (high blood sugar) because they destroy the insulin-making cells. Symptoms can include feeling thirsty and hungry, and having to urinate often. More often, cancer can lead to small changes in blood sugar levels that don’t cause symptoms of diabetes but can still be detected with blood tests.

Signs and symptoms of pancreatic neuroendocrine tumors:

Pancreatic neuroendocrine tumors (NETs) often release excess hormones into the bloodstream. Different types of tumors make different hormones, which can lead to different symptoms.

Gastrinomas

These tumors make gastrin, a hormone that tells the stomach to make more acid. Too much gastrin causes a condition known as Zollinger-Ellison syndrome, in which the stomach makes too much acid. This leads to stomach ulcers, which can cause pain, nausea, and loss of appetite. Severe ulcers can start bleeding. If the bleeding is mild, it can lead to anemia (too few red blood cells), which can cause symptoms like feeling tired and being short of breath. If the bleeding is more severe, it can make stool black and tarry. Severe bleeding can itself be life-threatening.

If the stomach acid reaches the small intestine, it can damage the cells of the intestinal lining and break down digestive enzymes before they have a chance to digest food. This can cause diarrhea and weight loss.

Glucagonomas

These tumors make glucagon, a hormone that increases glucose (sugar) levels in the blood. Most of the symptoms that can be caused by a glucagonoma are mild and are more often caused by something else.

Excess glucagon can raise blood sugar, sometimes leading to diabetes. This can cause symptoms such as feeling thirsty and hungry, and having to urinate often.

People with these tumors can also have problems with diarrhea, weight loss, and malnutrition. The nutrition problems can lead to symptoms like irritation of the tongue (glossitis) and the corners of the mouth (angular cheilitis).

The symptom that brings most people with glucagonomas to their doctor is a rash called necrolytic migratory erythema. This is a red rash with swelling and blisters that often travels from place to place on the skin.

Insulinomas

These tumors make insulin, which lowers blood glucose levels. Too much insulin leads to low blood sugar (hypoglycemia), which can cause symptoms like weakness, confusion, sweating, and rapid heartbeat. When blood sugar gets very low, it can lead to a person passing out or even going into a coma and having seizures.

Somatostatinomas

These tumors make somatostatin, which helps regulate other hormones. Symptoms of this type of tumor can include belly pain, nausea, poor appetite, weight loss, diarrhea, symptoms of diabetes (feeling thirsty and hungry, and having to urinate often), and jaundice (yellowing of the skin and eyes).

The early symptoms of a somatostatinoma tend to be mild and are more often caused by other things, so these tumors tend to be diagnosed at an advanced stage. Often, they are not found until they spread to the liver, when they cause problems like jaundice and pain.

Which treatments are used for pancreatic cancer?

Depending on the type and stage of the cancer and other factors, treatment options for people with pancreatic cancer can include:

  • Surgery
  • Ablation or embolization treatments
  • Radiation therapy
  • Chemotherapy and other drugs

Pain control is also an important part of treatment for many patients.

Sometimes, the best option might include more than one type of treatment. To learn about the most common approaches to treating these cancers, see Treating pancreatic cancer, based on the extent of the cancer.

For pancreatic neuroendocrine tumors (NETs), treatment options might include surgery, ablation or embolization treatments, radiation therapy, or different types of medicines. For more on how these tumors are treated, see Treating pancreatic neuroendocrine tumors, based on the extent of the tumor.

Cervical Polyps: Causes, symptoms and treatments

The cervix is a tubelike channel that connects the uterus to the vagina. Cervical polyps are growths that usually appear on the cervix where it opens into the vagina. Polyps are usually cherry-red to reddish-purple or grayish-white. They vary in size and often look like bulbs on thin stems. Cervical polyps are usually not cancerous (benign) and can occur alone or in groups. Most polyps are small, about 1 centimeter to 2 centimeters long. Because rare types of cancerous conditions can look like polyps, all polyps should be removed and examined for signs of cancer.

The cause of cervical polyps is not well understood, but they are associated with inflammation of the cervix. They also may result from an abnormal response to the female hormone estrogen.

Cervical polyps are relatively common, especially in women older than 20 who have had at least one child. They are rare in girls who have not started menstruating. There are two types of cervical polyps:

  • Ectocervical polyps can develop from the outer surface layer cells of the cervix. They are more common in postmenopausal women.
  • Endocervical polyps develop from cervical glands inside the cervical canal. Most cervical polyps are endocervical polyps, and are more common in premenopausal women.

Symptoms

Cervical polyps may not cause any symptoms. However, you may experience:

  • Discharge, which can be foul-smelling if there is an infection
  • Bleeding between periods
  • Heavier bleeding during periods
  • Bleeding after intercourse

Diagnosis

If you have a cervical polyp, you probably won’t be able to feel it or see it. Cervical polyps are discovered during routine pelvic exams or evaluations for bleeding or while getting a Pap test.

Expected Duration

Sometimes a polyp will come off on its own during sexual intercourse or menstruation. However, most polyps need to be removed to treat any symptoms and to evaluate the tissue for signs of cancer, which is rare.

 

Cervical Polyps

 

Prevention

Visit your doctor for an annual Pap test and for regular pelvic exams. A direct examination is the best way to identify cervical polyps.

Treatment

Cervical polyps are removed surgically, usually in a doctor’s office. The doctor will use a special instrument, called a polyp forceps, to grasp the base of the polyp stem and then gently pluck the polyp with a gentle, twisting motion. Bleeding is usually brief and limited. Nonprescription, mild pain medication such as acetaminophen (Tylenol and others) or ibuprofen (Advil, Motrin and others) can help to relieve discomfort or cramping during or after the procedure.

The polyp or polyps are sent to a laboratory for examination. You may receive antibiotics if the polyp shows signs of infection. If the polyp is cancerous, treatment will depend on the extent and type of cancer.

Large polyps and polyp stems that are very broad usually need to be removed in an operating room using local, regional or general anesthesia. You will not need to stay in the hospital overnight. Cervical polyps may grow in the future from different areas of the cervix, usually not from the original site. Regular pelvic examination will help to identify and treat polyps before they cause symptoms.

When To Call a Professional

If you experience vaginal discharge, bleeding after intercourse, or bleeding between periods, make an appointment to see your doctor as soon as possible for a pelvic exam.

Prognosis

The outlook is excellent. The vast majority of cervical polyps are not cancerous. Once removed, polyps usually don’t come back.

 

Stem cells and Procedures

Humans are the most advanced in the order of creation, they have been gifted with the intellect which they have been using in different fields and helping mankind make his life easier and simpler. With the advance in technology medicine was not far behind. The so called “incurable diseases” started finding a cure, psychiatric patients were unshackled after the discovery of neurotransmitters responsible for psychiatric illnesses. Antibiotics and vaccines started curing and preventing serious infectious diseases.

However the neuro-degenerative diseases such as dementia, MNDs, spinal cord injury, parkinsonism, cerebral palsy etc., still are in search of that elusive drug. But with the discovery of stem cell therapy the hitherto “elusive drug” the magic remedy has been found which has come to salvage scores of patients suffering from these debilitating illnesses.

What is stem cell?
Stem cells can be called as the ‘mother cells’. They originate from the developing embryo and differentiate into different types of cells for example the heart muscle, the liver, brain, skin, bone etc. Etc., They are known as progenitors cells since they lead to creation of new cells.

When these stem cells are transplanted into the body they migrate to the injured areas in the body , get attached there and transform themselves into the tissue desired and replace the damaged one.
This is the theory behind the use of stem cells in most of the neuro-degenerative and autoimmune disorders.

Procedures:

Essentially there are two types of stem cell therapy:

  • Autologous therapy where the patient is given stem cells derived from his own bone marrow, or adipose (fat) tissue.
  • Allogenic therapy where the donor cells are used ( not the patient himself but some other persons cells are transplanted)

 

What are Keloids: Symptoms, Treatment & Prevention

Keloids are raised overgrowths of scar tissue that occur at the site of a skin injury. They occur where trauma, surgery, blisters, vaccinations, acne or body piercing have injured the skin. Less commonly, keloids may form in places where the skin has not had a visible injury. Keloids differ from normal mature scars in composition and size. Some people are prone to keloid formation and may develop them in several places.

Keloids

Keloids are more common in African-Americans. They are seen most commonly on the shoulders, upper back and chest, but they can occur anywhere. When a keloid is associated with a skin incision or injury, the keloid scar tissue continues to grow for a time after the original wound has closed, becoming larger and more visible until it reaches a final size. They generally occur between 10 and 30 years of age and affect both sexes equally, although they may be more common among young women with pierced ears. Keloids may form over the breastbone in people who have had open heart surgery.

Symptoms:

Keloids usually appear in areas of previous trauma but may extend beyond the injured area. They are shiny, smooth and rounded skin elevations that may be pink, purple, or brown. They can be doughy or firm and rubbery to the touch, and they often feel itchy, tender or uncomfortable. They may be unsightly. A large keloid in the skin over a joint may interfere with joint function.

Expected Duration:

Keloids may continue to grow slowly for weeks, months or years. They eventually stop growing but do not disappear on their own. Once a keloid develops, it is permanent unless removed or treated successfully. It is common for keloids that have been removed or treated to return.

Prevention

People who are prone to keloids should avoid cosmetic surgery. When surgery is necessary in such people, doctors can take special precautions to minimize the formation of keloids at the site of the incision. Examples of techniques that might be used to minimize keloid formation include covering the healing wound with hypoallergenic paper tape for several weeks after surgery, covering the wound with small sheets made of a silicone gel after the surgery, or using corticosteroid injections or radiation treatments at the site of the surgical wound at the beginning of the healing period.

Treatment

There is no single treatment for keloids, and most treatments do not give completely satisfying results. Two or more treatments may be combined. If you decide to pursue treatment for a keloid scar, you will have the best results if you start treatment soon after the keloid appears. Available treatments include:

  • Removal with conventional surgery — This unreliable technique requires great care, and keloids that return after being removed may be larger than the original. Keloids return in more than 45% of people when they are removed surgically. Keloids are less likely to return if surgical removal is combined with other treatments.
  • Dressings — Moist wound coverings made of silicone gel sheets have been shown in studies to sometimes reduce the size of keloids over time. This treatment is safe and painless.
  • Corticosteroid injections — Injections with triamcinolone acetonide or another corticosteroid medicine typically are repeated at intervals of four to six weeks. This treatment can often reduce keloid size and irritation, but injections are uncomfortable.
  • Compression — This involves using a bandage or tape to apply continuous pressure 24 hours a day for a period of six to 12 months. Such compression can cause a keloid to become smaller. For keloids that form at the site of an ear piercing, a clip known as a “Zimmer splint” usually reduces keloid size by at least 50% after one year of compression. Zimmer splints that resemble earrings are available.
  • Cryosurgery — This freezing treatment with liquid nitrogen is repeated every 20 to 30 days. It can cause a side effect of lightening the skin color, which limits this treatment’s usefulness.
  • Radiation therapy — This therapy is controversial because radiation increases the risk of cancer. Radiation treatments may reduce scar formation if they are used soon after a surgery, during the time a surgical wound is healing.
  • Laser therapy — This is an alternative to conventional surgery for keloid removal. There is no good evidence that keloids are less likely to return after laser therapy than after regular surgery.
  • Experimental treatments — One treatment showing promise is injecting keloid scars with medicines that were developed to treat autoimmune illnesses or cancers. Treatments with these medicines (various types of interferon and the chemotherapy agents 5-fluorouracil and bleomycin) will need to be evaluated further before they are appropriate for use outside of research studies.

 

Cirrhosis: Causes, Symptoms and Treatments

Cirrhosis:

Cirrhosis is a complication of many liver diseases that is characterized by abnormal structure and function of the liver. The diseases that lead to cirrhosis do so because they injure and kill liver cells, and the inflammation and repair that is associated with the dying liver cells causes scar tissue to form. The liver cells that do not die multiply in an attempt to replace the cells that have died. This results in clusters of newly-formed liver cells (regenerative nodules) within the scar tissue. There are many causes of cirrhosis; they include chemicals (such as alcohol, fat, and certain medications), viruses, toxic metals (such as iron and copper that accumulate in the liver as a result of genetic diseases), and autoimmune liver disease in which the body’s immune system attacks the liver.
Cirrhosis is a consequence of chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue and regenerative nodules (lumps that occur as a result of a process in which damaged tissue is regenerated), leading to loss of liver function. Cirrhosis is most commonly caused by alcoholism, hepatitis B and C, and fatty liver disease, but has many other possible causes. Some cases are idiopathic (i.e., of unknown cause). Ascites (fluid retention in the abdominal cavity) is the most common complication of cirrhosis, and is associated with a poor quality of life, increased risk of infection, and a poor long-term outcome. Other potentially life-threatening complications are hepatic encephalopathy (confusion and coma) and bleeding from esophageal varices.

Major Causes Of Liver Cirrhosis:

  1. Chronic alcohol consumption – Consuming alcohol regularly causes the development of liver cirrhosis. This is the most important and common cause of liver cirrhosis. 30 % of the individuals who drink 8 to 14 ounces of alcholol ( hard drinks) for about 10-12 years can develop liver cirrhosis. In the beginning, it is fatty liver but slowly the fat keeps on accumulating over the liver cells and hampering their functions, suffocating them and more alcohol keeps on injuring them, leading to their death and scarring.
  2. Hepatitis A,B, C, D ,E , F ,G – Although hepatitis A has not been implicated as major reason for cirrhosis of the liver but more deadly hepatitis types like B, C and G are considered devastating for the liver. The virus can remain dormant for years but can attack anytime leading to fulminant hepatic failure. Treatment of hepatitis is very important to prevent cirrhosis at later stage. Hepatitis is one of the leading causes of liver cirrhosis.
  3. Too many drugs consumed for other diseases - for example for gout, for arthritis, for skin, for allergies and so on – people keep on consuming various drugs which are metabolized in liver but ignoring the burden on liver, they keep on popping pills and putting pressure on liver, causing liver cirrhosis.
  4. Non alcoholic fatty liver disease - This disease can be caused by metabolic syndrome, diabetes, and obesity. Obesity also puts a lot of burden on the liver and slowly causes cirrhosis.
  5. Cryptogenic Cirrhosis - It is one of the major reasons for liver transplant now a days. It is called cryptogenic cirrhosis as it is not explainable. The reasons are not known to current day medical science and tht’s why it is called cryptogenic. Usually it is due to long standing obesity, diabetes and insulin resistance.
  6. Primary biliary cirrhosis is a liver disease caused by disturbance of immune system, when the immune system starts attacking our own bile ducts in the lvier. The bile ducts carries the bile From liver to the intestine. This bile helps in digestion and contains bilirubin. If these bile duct is blocked due to certain reasons, the process of liver destruction starts. Slowly as the liver cells are being destroyed, the whole liver becomes inflamed and a process of hepatic cells damage starts leading to accumulate of waste products in the liver and causing more damage.

What Are The Signs And Symptoms Of Liver Cirrhosis?

  1. Weight loss and loss of appetite
  2. Weakness and fatigue
  3. Jaundice
  4. Accumulation of water in abdominal cavity called Ascites
  5. Encephalopathy
  6. Bleeding in esophagus due to backlog/ pooling of blood. Also called esophageal varices
  7. Redness of the palm.
  8. Duputryen’s contracture.
  9. Clubbing of the fingers
  10. Enlargement of parotid and lachrymal gland
  11. Red spidery patches on the skin.
  12. Spider naevi – around naval
  13. Decreased body hair
  14. Gynaecomastia in men
  15. Hirsuitism, menstrual abnormalities in females
  16. Enlarged spleen.

Treatments:

Cirrhosis is generally irreversible, and treatment usually focuses on preventing progression and complications. In advanced stages of cirrhosis the only option is a liver transplant.

2D echo cardiogram: Procedures

An echocardiogram uses sound waves to produce images of your heart. This commonly used test allows your doctor to see how your heart is beating and pumping blood. Your doctor can use the images from an echocardiogram to identify various abnormalities in the heart muscle and valves.

Depending on what information your doctor needs, you may have one of several types of echocardiograms. Each type of echocardiogram has few risks involved.

Why it’s Done:

  • Transthoracic echocardiogram. This is a standard, noninvasive echocardiogram. A technician (sonographer) spreads gel on your chest and then presses a device known as a transducer firmly against your skin, aiming an ultrasound beam through your chest to your heart. The transducer records the sound wave echoes your heart produces. A computer converts the echoes into moving images on a monitor. If your lungs or ribs block the view, a small amount of intravenous dye may be used to improve the images.
  • Transesophageal echocardiogram. If it’s difficult to get a clear picture of your heart with a standard echocardiogram, your doctor may recommend a transesophageal echocardiogram. In this procedure, a flexible tube containing a transducer is guided down your throat and into your esophagus, which connects your mouth to your stomach. From there, the transducer can obtain more-detailed images of your heart. Your throat will be numbed, and you’ll have medications to help you relax during a transesophageal echocardiogram.
  • Doppler echocardiogram. When sound waves bounce off blood cells moving through your heart and blood vessels, they change pitch. These changes (Doppler signals) can help your doctor measure the speed and direction of the blood flow in your heart. Doppler techniques are used in most transthoracic and transesophageal echocardiograms, and they can check blood flow problems and blood pressures in the arteries of your heart that traditional ultrasound might not detect. Sometimes, the blood flow shown on the monitor is colorized to help your doctor pinpoint any problems (color flow echocardiogram).
  • Stress echocardiogram. Some heart problems — particularly those involving the coronary arteries that supply blood to your heart muscle — occur only during physical activity. For a stress echocardiogram, ultrasound images of your heart are taken before and immediately after walking on a treadmill or riding a stationary bike. If you’re unable to exercise, you may get an injection of a medication to make your heart work as hard as if you were exercising.

Results:

Your doctor will look for healthy heart valves and chambers, as well as normal heartbeats. Information from the echocardiogram may show:

  • Heart size. Weakened or damaged heart valves, high blood pressure or other diseases can cause the chambers of your heart to enlarge. Your doctor can use an echocardiogram to evaluate the need for treatment or monitor treatment effectiveness.
  • Pumping strength. An echocardiogram can help your doctor determine your heart’s pumping strength. Specific measurements may include the percentage of blood that’s pumped out of a filled ventricle with each heartbeat (ejection fraction) or the volume of blood pumped by the heart in one minute (cardiac output). If your heart isn’t pumping enough blood to meet your body’s needs, heart failure may be a concern.
  • Damage to the heart muscle. During an echocardiogram, your doctor can determine whether all parts of the heart wall are contributing normally to your heart’s pumping activity. Parts that move weakly may have been damaged during a heart attack or be receiving too little oxygen. This may indicate coronary artery disease or various other conditions.
  • Valve problems. An echocardiogram shows how your heart valves move as your heart beats. Your doctor can determine if the valves open wide enough for adequate blood flow or close fully to prevent blood leakage. Abnormal blood flow patterns and certain conditions, such as aortic valve stenosis — when the heart’s aortic valve is narrowed — can be detected as well.
  • Heart defects. Many heart defects can be detected with an echocardiogram, including problems with the heart chambers, abnormal connections between the heart and major blood vessels, and complex heart defects that are present at birth. Echocardiograms can even be used to monitor a baby’s heart development before birth.

 

Risks:

There are few risks involved in a standard transthoracic echocardiogram. You may feel some discomfort similar to pulling off an adhesive bandage when the technician removes the electrodes placed on your chest during the procedure.

If you have a transesophageal echocardiogram, your throat may be sore for a few hours afterward. Rarely, the tube may scrape the inside of your throat. Your oxygen level will be monitored during the exam to check for any breathing problems caused by sedation medication.

During a stress echocardiogram, exercise or medication — not the echocardiogram itself — may temporarily cause an irregular heartbeat. Serious complications, such as a heart attack, are rare.

 

 

Dyslexia: Causes, Symptoms & Treatments

Dyslexia is a specific reading disability due to a defect in the brain’s processing of graphic symbols.

It is a learning disability that alters the way the brain processes written material and is typically characterized by difficulties in word recognition, spelling, and decoding.

People with dyslexia have problems with reading comprehension.

The National Center for Learning Disabilities says that dyslexia is a neurological and often genetic condition, and not the result of poor teaching, instruction, or upbringing.

Dyslexia is not linked to intelligence.

Symptoms of dyslexia

The most common signs and symptoms associated with dyslexia are:

  • Learning to read – the child, despite having normal intelligence and receiving proper teaching and parental support, has difficulty learning to read.
  • Milestones reached later – the child learns to crawl, walk, talk, and ride a bicycle later than the majority of other kids.
  • Speech – apart from being slow to learn to speak, the child commonly mispronounces words, finds rhyming extremely challenging, and does not appear to distinguish between different word sounds.
  • Slow at learning sets of data – at school, the child takes much longer than the other children to learn the letters of the alphabet and how they are pronounced. There may also be problems remembering the days of the week, months of the year, colors, and some arithmetic tables.
  • Coordination – the child may seem clumsier than their peers. Catching a ball may be difficult.
  • Left and right – the child commonly gets “left” and “right” mixed up.
  • Reversal – numbers and letters may be reversed without realizing.
  • Spelling – might not follow a pattern of progression seen in other children. The child may learn how to spell a word today and completely forget the next day.
  • Phonology problems – phonology refers to the speech sounds in a language. If a word has more than two syllables, phonology processing becomes much more difficult. For example, with the word “unfortunately” a person with dyslexia may be able to process the sounds “un” and “ly,” but not the ones in between.
  • Concentration span – children with dyslexia commonly find it hard to concentrate. Many adults with dyslexia say this is because, after a few minutes of non-stop struggling, the child is mentally exhausted. A higher number of children with dyslexia also have ADHD (attention deficit hyperactivity disorder), compared with the rest of the population.
  • Sequencing ideas – when a person with dyslexia expresses a sequence of ideas, they may seem illogical.
  • Autoimmune conditions – people with dyslexia are more likely to develop immunological problems, such as hay fever, asthma, eczema, and other allergies.

 

Causes of dyslexia

A child doing homework
A child with dyslexia may have more difficulty than usual in reading, spelling, and concentrating.

Specialist doctors and researchers are not sure what causes a person to develop dyslexia.

Some evidence points to the possibility that the condition is inherited, as dyslexia often runs in families.

Genetic causes of dyslexia

A team at the Yale School of Medicine found that defects in a gene, known as DCDC2, were associated with problems in reading performance.

Treatments for dyslexia

It is important for family members and the person with dyslexia to remember that dyslexia is not a disease. We live in a society where reading and writing are integral parts of everyday life – interventions that help people with dyslexia are aimed at improving their coping skills.

There is currently no “cure” for dyslexia. There are, however, a range of specialist and well-targeted interventions that can help children and adults improve their reading and writing skills.

The sooner a child is diagnosed and receives support, the more likely he or she will achieve long-term improvements.

Psychological testing helps the teacher develop a better-targeted teaching program for the child.

A teacher who is trained in helping children with dyslexia will use a range of techniques to improve the child’s reading skills. These techniques usually involve tapping into the child’s senses, including touch, vision, and hearing.

Some children find that tracing their finger around the shape of letters helps them process data more effectively.

Parkinson’s Disease: Symptoms & Treatments

Parkinson’s disease is a movement disorder that progresses slowly. Some people will first notice a sense of weakness, difficulty walking, and stiff muscles. Others may notice a tremor of the head or hands. Parkinson’s is a progressive disorder and the symptoms gradually worsen. The general symptoms of Parkinson’s disease include:

  • Slowness of voluntary movements, especially in the initiation of such movements as walking or rolling over in bed
  • Decreased facial expression, monotonous speech, and decreased eye blinking
  • A shuffling gait with poor arm swing and stooped posture
  • Unsteady balance; difficulty rising from a sitting position
  • Continuous “pill-rolling” motion of the thumb and forefinger
  • Abnormal tone or stiffness in the trunk and extremities
  • Swallowing problems in later stages
  • Lightheadedness or fainting when standing (orthostatic hypotension).

Treatments:

What Is Pallidotomy?

It is thought that the part of the brain called the globus pallidus becomes overactive in Parkinson’s disease. This overactivity acts like a brake and slows or diminishes bodily movement. Pallidotomy surgery permanently destroys the overactive globus pallidus to lessen the symptoms of Parkinson’s disease. This treatment can eliminate rigidity and significantly reduce tremor, bradykinesia, and balance problems. Pallidotomy can also enhance the effect of medication in people with an advanced form of the disease.

What Is Thalamotomy?

It is thought that the abnormal brain activity that causes tremor is processed through the thalamus. Thalamotomy destroys part of the thalamus to block the abnormal brain activity from reaching the muscles and causing tremor. Because thalamotomy is used only to control tremors, it is not generally recommended as a treatment for Parkinson’s disease.

parkinson

 

Ankle disorders: Causes, symptoms & Treatments

What causes ankle disorders?

The causes of ankle disorders vary, and can include running, jumping, and overuse. Other common causes of ankle sprains and fractures include:

  • twisting or rotating the ankle beyond the normal range of motion
  • tripping or falling
  • landing on the foot with increased force

Other injuries that can lead to tendonitis in the ankle or Achilles tendonitiscan be caused by:

  • lack of conditioning for the muscles in the leg and foot
  • excess strain on the Achilles tendon, the tendon that connects your calf muscles to your heel
  • bone spurs in the heel that rub on the Achilles tendon
  • untreated flat feet leading to additional stress on the posterior tibialis tendon

Different types of arthritis (inflammation of joints and tissues) can also affect the foot and ankle:

  • Osteoarthritis is a degenerative type of arthritis that typically begins in middle age and slowly progresses. Over time, cartilage between your bones becomes worn down. This results in pain and stiffness in your joints.
  • Rheumatoid arthritis is an autoimmune inflammatory disease. It occurs when your body mistakenly attacks its own healthy tissues. RA affects your joints and also destroys cartilage.
  • Post-traumatic arthritis occurs after an injury to your foot or ankle. Stress from the injury can cause your joints to become stiff or inflamed, even years after the injury occurred.

What are the symptoms of ankle disorders?

The symptoms of ankle disorders will vary based on the specific type of injury. Common symptoms include:
  • pain
  • swelling
  • stiffness
  • problems moving the ankle
  • inability to put any weight on the ankle
  • difficulty walking
  • bruising

Tendonitis and Achilles tendonitis may produce similar symptoms, but can be accompanied by:

  • pain along the back of the heel that gets worse throughout the day
  • thickening of the tendon
  • swelling that gets worse with physical activity
  • loud popping sounds at the back of the heel, signaling a ruptured tendon. If this occurs, seek emergency medical attention.

Treatments:

Treatment will depend on your condition and your symptoms. Treatments can include nonsurgical and surgical options. Nonsurgical options involve:

  • taking pain medications
  • taking medications to reduce swelling and inflammation, like aspirin or ibuprofen
  • resting and elevating your ankle
  • applying ice packs to reduce swelling
  • wearing compression bandages or casts to immobilize your ankle
  • getting cortisone (steroid) injections to reduce pain and swelling

Severe fractures or ruptured tendons may require surgical treatment. Surgical procedures used to treat ankle disorders include:

  • reconstruction to rebuild bones, joints, tendons, and ligaments in your ankle
  • removal of damaged tissue (debridement)
  • lengthening the calf muscles to reduce pressure on your Achilles tendon
  • fusion of the bones in your ankle to make it more stable (arthrodesis)
  • replacement of your ankle joint (arthroplasty).

 

Pages:1...52535455565758...81